CEREBRAL AMYLOID ANGIOPATHY AS A CAUSE OF MULTIPLE INTRACEREBRAL HEMORRHAGES
CEREBRAL AMYLOID ANGIOPATHY AS A CAUSE OF MULTIPLE INTRACEREBRAL HEMORRHAGES
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DOI：
10.1212/wnl.34.6.730
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发表时间：
1984-01-01
期刊：
影响因子：
9.9
通讯作者：
VANDERHAEGHEN, JJ
中科院分区：
文献类型：
--
作者：
GILLES, C;BRUCHER, JM;VANDERHAEGHEN, JJ
本文报告了6例脑淀粉样血管病合并脑膜出血的临床和病理表现。一名患者曾经历过脑膜出血，两名患者患有慢性高血压：在所有尸检的大脑中发现的多发性新鲜血肿总是能幸免于基底节和脑干，血管损伤也是如此，这些病变大多是皮质和脑膜。在痴呆尸检中发现广泛的阿尔茨海默病S病病变，临床诊断出血性淀粉样脑血管病最显著的特征是在没有高血压的情况下，在不寻常的部位出现多发性出血。
Clinical and pathologic findings in 6 autopsies and 5 biopsies of cerebral amyloid angiopathy associated with cerebromeningeal hemorrhages are presented. One patient experienced a previous meningeal hemorrhage, 2 had chronic hypertension: the multiple fresh hematomas found in all the autopsied brains always spared the basal ganglia and brainstem, as did vascular lesions, which were mostly cortical and meningeal. Extensive lesions of Alzheimer''s disease were found in the autopsied cases with dementia. The most significant feature for clinical diagnosis of hemorrhagic cerebral amyloid angiopathy is the presence of multiple hemorrhages in unusual locations in the absence of hypertension.