Could Activity Modifications Indicate Physical Decline Among Adults With Symptomatic Knee Osteoarthritis?
Could Activity Modifications Indicate Physical Decline Among Adults With Symptomatic Knee Osteoarthritis?
复制标题
活动改变是否表明患有症状性膝骨关节炎的成年人身体出现衰退？
DOI：
10.1097/phm.0000000000000802
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发表时间：
2018
影响因子：
3
通讯作者：
Wang,Chenchen
中科院分区：
文献类型：
--
作者：
Lee,AugustineC;Bloch,RinaM;Harvey,WilliamF;Driban,JeffreyB;Price,LoriLyn;Han,Xingyi;Wang,Chenchen
目的移动性活动改变表明早期功能丧失是社区老年人未来衰退的前兆。然而，很少有证据表明，活动改变是否表明患有症状性骨关节炎的成年人身体健康较差，这是导致残疾的主要原因。我们的目的是调查患者报告的活动能力改善是否表明患有症状性膝骨性关节炎的成年人的身体健康状况较差。设计对随机试验数据进行二次横断面分析。使用临床前残疾问卷将参与者分为以下三类：困难组、改良组和行走/爬楼梯无困难组。采用Kruskal Wallis和χ-2检验比较各组的临床因素。结果在121名参与者(中位年龄=60岁；73%女性；60%白人)中，不到10%的人修改了步行/爬楼梯。与没有步行困难的参与者相比，改良式步行的参与者的平衡(P=0.01)和整体健康(P=0.01)显著降低，膝关节疼痛(P=0.05)和身体残疾(P=0.04)也明显增加。改良爬楼梯组步行距离明显小于非爬楼梯困难组(P=0.03)。结论活动度改良可能预示有症状的膝骨性关节炎患者的身体健康早期受损。如果得到证实，患者报告的活动修改可能会增强骨关节炎的症状评估，并使人们能够更好地了解残疾过程。
ObjectivesMobility activity modifications indicate early functional losses that act as precursors to future declines among community-dwelling older adults. However, there is scarce evidence on whether activity modifications indicate poorer physical health among adults with symptomatic osteoarthritis, a major cause of disability. Our purpose was to investigate whether patient-reported mobility activity modifications indicated poorer physical health among adults with symptomatic knee osteoarthritis.DesignSecondary cross-sectional analysis of randomized trial data was performed. Preclinical Disability Questionnaire was used to group participants into the following three categories: difficulty, modified, and no difficulty walking/stair climbing. Kruskal Wallis and χ 2 tests were used to compare clinical factors across groups.ResultsAmong 121 participants (median age= 60 yrs; 73% female; 60% white), less than 10% had modified walking/stair climbing. Compared with those with no walking difficulty, participants with modified walking had significantly less balance (P= 0.01) and global health (P= 0.01) as well as greater knee pain (P= 0.05) and physical disability (P= 0.04). Those with modified stair climbing had significantly smaller walking distances (P= 0.03) compared with those with no difficulty stair climbing.ConclusionsActivity modifications may signal early impairments in physical health among people with symptomatic knee osteoarthritis. If confirmed, patient-reported activity modifications may enhance symptom evaluation in osteoarthritis and enable a better understanding of the disablement process.