Peer navigation for smoking cessation in smokers with HIV: Protocol for a randomized clinical trial.
Peer navigation for smoking cessation in smokers with HIV: Protocol for a randomized clinical trial.
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DOI：
10.1016/j.cct.2021.106435
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发表时间：
2021-11
影响因子：
2.2
通讯作者：
Kahler CW
中科院分区：
文献类型：
--
作者：
Cioe PA;Pinkston M;Tashima KT;Kahler CW
艾滋病毒感染者的吸烟率很高（40%），戒烟率仍然很低。缺乏社会支持和对尼古丁替代疗法（NRT）的依从性差与不良戒烟结果有关;因此，这两个因素都是戒烟干预的可能目标。同伴导航员已被纳入艾滋病毒护理，并取得了巨大成功，以改善抗逆转录病毒治疗的参与和坚持。然而，没有临床试验评估PN提供社会支持和改善NRT戒烟依从性的潜力。我们开发了一种治疗方案，通过将PN纳入戒烟计划，以社会支持、依从性和自我效能为目标。这项随机试验将测试与标准治疗相比，这种方法是否会在12周和24周时导致更高的7天点戒烟率。72名HIV吸烟者将随机接受同伴导航戒烟社会支持（PNSS-S）或标准戒烟咨询。所有参与者将与护士会面进行戒烟咨询会议，其中包括FDA批准的戒烟药物治疗的讨论。分配到PNSS-S的受试者将在12周内每周收到PN的电话。PN将讨论戒烟准备、使用药物戒烟、常见的戒烟障碍、高风险情况、滑倒管理和保持禁欲。将在基线预约后第4、12和24周测量戒烟结果。这项研究的结果将提供初步证据，证明将基于同伴导航的干预纳入戒烟治疗是否可以改善PWH的戒烟结果。
Smoking prevalence in persons with HIV (PWH) is high (40%) and cessation rates remain low. Lack of social support and poor adherence to nicotine replacement therapy (NRT) are related to poor cessation outcomes; thus, both factors represent possible targets for smoking cessation interventions. Peer navigators (PNs) have been integrated into HIV care with great success to improve engagement and adherence to antiretroviral therapy. However, no clinical trial has evaluated the potential for PNs to provide social support and improve NRT adherence for smoking cessation. We developed a treatment protocol that targets social support, adherence, and self-efficacy for quitting by incorporating PNs into a smoking cessation program. This randomized trial will test whether this approach results in higher rates of 7-day point prevalence abstinence at 12- and 24-weeks, compared to standard treatment. Seventy-two smokers with HIV will be randomized to either Peer Navigation Social Support for smoking cessation (PNSS-S) or standard cessation counseling. All participants will meet with a nurse for a smoking cessation counseling session, which will include discussion of FDA-approved cessation pharmacotherapy. Participants assigned to PNSS-S will receive weekly phone calls from the PN for 12 weeks. The PN will address readiness to quit, using medication to quit, common barriers to cessation, high risk situations, slip management, and maintaining abstinence. Smoking cessation outcomes will be measured at 4, 12, and 24 weeks following the baseline appointment. Results from this study will provide preliminary evidence of whether incorporating a peer navigator-based intervention into smoking cessation treatment can improve smoking cessation outcomes in PWH.
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