Clostridium difficile--more difficult than ever.
Clostridium difficile--more difficult than ever.
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DOI：
10.1056/nejmra0707500
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发表时间：
2008-10-30
期刊：
影响因子：
--
通讯作者：
LaMont, J Thomas
中科院分区：
文献类型：
--
作者：
Kelly, Ciaran P;LaMont, J Thomas
由于这种机会性病原体的突变，c感染。困难已经变得更加普遍和更加致命。本文总结了最近这种感染的流行病学变化，并解释了已知的疾病严重程度的变化和对治疗的反应。作者讨论了使用新的抗生素，益生菌，免疫疗法，甚至细菌疗法。
Because of mutations in this opportunistic pathogen, infections withC. difficilehave become both more prevalent and more virulent. This article summarizes recent changes in the epidemiology of this infection and explains what is known about the changes in disease severity and the response to therapy. The authors discuss the use of new antibiotics, probiotics, immunotherapy, and even bacteriotherapy.