Blood-clotting-inspired reversible polymer-colloid composite assembly in flow
Blood-clotting-inspired reversible polymer-colloid composite assembly in flow
复制标题
DOI：
10.1038/ncomms2326
复制
发表时间：
2013-01-01
影响因子：
16.6
通讯作者：
Alexander-Katz, Alfredo
中科院分区：
文献类型：
--
作者：
Chen, Hsieh;Fallah, Mohammad A.;Alexander-Katz, Alfredo
凝血是在损伤部位组装止血栓的过程。这种塞的形成本质上是一种（生物）聚合物-胶体复合材料，据信是由初始阶段的剪切流驱动的，与我们的直觉相反，它的组装在更强的流动条件下得到加强。在这里，受血液凝固的启发，我们表明聚合物-胶体复合材料在剪切流动中的组装是一个普遍的过程，可以定制以获得不同类型的聚集体，包括松散和密集的聚集体，以及流体动力诱导的“对数”型聚集体。该过程是高度可控和可逆的，主要取决于剪切速率和聚合物-胶体结合势的强度。我们的结果对聚合物-胶体复合材料的组装具有重要意义，这是一个具有巨大技术相关性的重要挑战。此外，流动驱动的可逆复合地层代表了非平衡自组装的新范式。
Blood clotting is a process by which a haemostatic plug is assembled at the site of injury. The formation of such a plug, which is essentially a (bio)polymer-colloid composite, is believed to be driven by shear flow in its initial phase, and contrary to our intuition, its assembly is enhanced under stronger flowing conditions. Here, inspired by blood clotting, we show that polymer-colloid composite assembly in shear flow is a universal process that can be tailored to obtain different types of aggregates including loose and dense aggregates, as well as hydrodynamically induced 'log'-type aggregates. The process is highly controllable and reversible, depending mostly on the shear rate and the strength of the polymer-colloid binding potential. Our results have important implications for the assembly of polymer-colloid composites, an important challenge of immense technological relevance. Furthermore, flow-driven reversible composite formation represents a new paradigm in non-equilibrium self-assembly.