Synthesis, RNA selective hybridization and high nuclease resistance of an oligonucleotide containing novel bridged nucleic acid with cyclic urea structure.
Synthesis, RNA selective hybridization and high nuclease resistance of an oligonucleotide containing novel bridged nucleic acid with cyclic urea structure.
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含有具有环状脲结构的新型桥接核酸的寡核苷酸的合成、RNA选择性杂交和高核酸酶抗性。
DOI:
10.1039/c0cc00154f
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发表时间:
2010
影响因子:
4.9
通讯作者:
S. Obika
中科院分区:
文献类型:
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作者:
M. Nishida;Takeshi Baba;T. Kodama;Aiko Yahara;T. Imanishi;S. Obika
A novel bridged nucleic acid bearing cyclic urea structure was successfully synthesized and introduced into oligonucleotide, displaying attractive characteristics of highly RNA selective hybridization ability and excellent resistance towards nuclease degradation.
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影响因子:
15
作者:
Rahman, S. M. Abdur;Seki, Sayori;Imanishi, Takeshi
通讯作者:
Imanishi, Takeshi
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DOI:
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发表时间:
2009
期刊:
Chem. Lett。 38
影响因子:
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作者:
S. M. A. Rahman;et al.
通讯作者:
et al.
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