Mechanical modeling of stents deployed in tapered arteries.
Mechanical modeling of stents deployed in tapered arteries.
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DOI：
10.1007/s10439-008-9582-0
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发表时间：
2008-12
影响因子：
3.8
通讯作者：
Moore, James E., Jr.
中科院分区：
文献类型：
--
作者：
Timmins, Lucas H.;Meyer, Clark A.;Moreno, Michael R.;Moore, James E., Jr.
支架与其所部署的动脉的生物力学相互作用是长期成功的潜在重要考虑因素。动脉对过度压力的不良反应和由此产生的损伤与再狭窄的发展有关。这些手术中经常遇到的复杂几何特征可能会混淆治疗。在某些情况下，期望在直径在支架长度上显著减小的区域上展开支架。本研究旨在评估锥形动脉中的最终动脉直径和周向应力，在锥形动脉中展开了两种不同的支架（一种坚硬，一种硬度较低）。假设动脉壁由应变硬化材料制成，承受较大变形，支架长度上直径减小10%。一个商业上可用的有限元代码被用来解决两个弹性体之间的接触问题。更硬的支架在动脉锥度上占主导地位，导致沿支架长度的最终直径沿着几乎恒定，应力非常高，特别是在远端。刚度较小的支架更紧密地遵循动脉的锥形轮廓，导致动脉壁应力较低。对于锥形动脉应用，应考虑更顺应性的支架，甚至可能排除锥形支架。
The biomechanical interaction of stents and the arteries into which they are deployed is a potentially important consideration for long-term success. Adverse arterial reactions to excessive stress and the resulting damage have been linked to the development of restenosis. Complex geometric features often encountered in these procedures can confound treatment. In some cases, it is desirable to deploy a stent across a region in which the diameter decreases significantly over the length of the stent. This study aimed to assess the final arterial diameter and circumferential stress in tapered arteries into which two different stents were deployed (one stiff and one less stiff). The artery wall was assumed to be made of a strain stiffening material subjected to large deformations, with a 10% decrease in diameter over the length of the stent. A commercially available finite element code was employed to solve the contact problem between the two elastic bodies. The stiffer stent dominated over arterial taper, resulting in a nearly constant final diameter along the length of the stent, and very high stresses, particularly at the distal end. The less stiff stent followed more closely the tapered contour of the artery, resulting in lower artery wall stresses. More compliant stents should be considered for tapered artery applications, perhaps even to the exclusion of tapered stents.
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影响因子：
3.8
作者：
HUMPHREY, JD;KANG, T;ANJANAPPA, M
通讯作者：
ANJANAPPA, M
影响因子：
2.4
作者：
Migliavacca, F;Petrini, L;Pietrabissa, R
通讯作者：
Pietrabissa, R
影响因子：
20.1
作者：
Rogers, C;Tseng, DY;Edelman, ER
通讯作者：
Edelman, ER
DOI：
10.1115/1.2246236
发表时间：
2006-10-01
影响因子：
1.7
作者：
Bedoya, Julian;Meyer, Clark A.;Moore, James E., Jr.
通讯作者：
Moore, James E., Jr.
影响因子：
3.8
作者：
Holzapfel, GA;Stadler, M;Schulze-Bauer, CAJ
通讯作者：
Schulze-Bauer, CAJ