Pityriasis rosea-like drug eruption due to nortriptyline in a patient with vulvodynia.
Pityriasis rosea-like drug eruption due to nortriptyline in a patient with vulvodynia.
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DOI：
10.1097/lgt.0b013e31825d7c5f
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发表时间：
2013-04
影响因子：
3.7
通讯作者：
Lindau ST
中科院分区：
文献类型：
--
作者：
Bangash HK;Finch T;Petronic-Rosic V;Sethi A;Abramsohn E;Lindau ST
Nortriptyline and other tricyclic anti-depressants (TCAs) are widely used in the treatment of depression. They are also used in chronic pain syndromes such as vulvodynia. We report a case of pityriasis rosea (PR)-like eruption in a young woman who was treated with oral nortriptyline for vulvodynia. The patient presented with photosenstivity and erythematous, well-defined, oval papules and patches, with fine collarettes of scale on the dorsal hands, upper arms and trunk. She showed a complete resolution of her rash with discontinuation of nortriptyline, thereby supporting the diagnosis of a drug-induced reaction. PR-like drug eruptions have been associated with numerous medications, including angiotensin converting enzyme inhibitors, anti-rheumatic drugs, lithium, and, more recently, biologics such as imatinib, adalimumab and etanercept. A literature review did not reveal an association between PR-like drug eruptions and tricyclic antidepressants such as nortriptyline. We report a case of PR-like drug reaction to nortriptyline for clinical interest.
