Frequency and presentation of depressive symptoms in patients with primary degenerative dementia.
Frequency and presentation of depressive symptoms in patients with primary degenerative dementia.
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原发性退行性痴呆患者抑郁症状的频率和表现。
DOI：
10.1176/ajp.144.1.41
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发表时间：
1987
期刊：
影响因子：
--
通讯作者：
C. Schweon
中科院分区：
文献类型：
--
作者：
L. Lazarus;N. Newton;B. Cohler;J. Lesser;C. Schweon
作者检查了推测患有原发性退行性痴呆的老年患者抑郁症状的频率和严重程度，并确定了为诊断抑郁症提供可靠依据的体征和症状。 44 名患者和 42 名对照受试者接受了采访，并根据汉密尔顿抑郁量表和山德士临床评估-老年量表进行了评分。其中九名患者表现出轻度抑郁症的症状，四名患者表现出中度抑郁症的症状，五名患者表现出重度抑郁症的症状。在评估抑郁症的心理症状而非植物症状的项目上，患者的得分明显高于对照组。这些发现强调了对原发性退行性痴呆患者伴随的抑郁症状保持高度怀疑的重要性。
The authors examined the frequency and severity of depressive symptoms in elderly patients with presumed primary degenerative dementia and identified the signs and symptoms that provide a reliable basis for diagnosing depression. Forty-four patients and 42 control subjects were interviewed and rated on the Hamilton Rating Scale for Depression and the Sandoz Clinical Assessment-Geriatric Scale. Nine of the patients demonstrated symptoms suggestive of mild, four of moderate, and five of severe depression. Patients had significantly higher scores than control subjects on items that assess intrapsychic rather than vegetative symptoms of depression. These findings underline the importance of maintaining a high index of suspicion for concomitant depressive symptoms in patients with primary degenerative dementia.