Sarcopenia Screened by the SARC-F Questionnaire and Physical Performances of Elderly Women: A Cross-Sectional Study
Sarcopenia Screened by the SARC-F Questionnaire and Physical Performances of Elderly Women: A Cross-Sectional Study
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DOI：
10.1016/j.jamda.2017.05.010
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发表时间：
2017-10-01
影响因子：
7.6
通讯作者：
Barreto, Philipe de Souto
中科院分区：
文献类型：
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作者：
Rolland, Yves;Dupuy, Charlotte;Barreto, Philipe de Souto
目的：在日常练习中筛查肌肉减少症可能具有挑战性。我们的目的是探讨SARC-F问卷是否是一个有效的筛选工具，肌肉减少症（定义由美国国立卫生研究院[FNIH]的标准基金会）。设计：横断面研究，研究对象：来自图卢兹和里昂骨质疏松症流行病学研究（EPIDOS）的3025名社区妇女（平均年龄：80.5 ± 3.9岁），既往无髋部骨折史。SAARC-F自我报告问卷评分范围为0 - 10：评分>= 4定义为肌肉减少症。FNIH标准使用握力（GS）和非典型瘦体重（ALM;通过DXA评估）除以体重指数（BMI）来定义肌肉减少症。结果的措施是以下性能为基础的测试：膝关节伸展的力量，6米的步态速度，并重复椅子站立测试。使用自举多元线性回归模型检查肌肉减少症与基于性能的测试的关联;调整后的R-2确定的百分比变化为每个结果解释的model.Results：肌肉减少症的患病率为16.7%（n = 504）根据SARC-F问卷和1.8%（n = 49）使用FNIH标准。SARC-F诊断肌减少症（FNIH标准定义）的敏感性和特异性分别为34%和85%。SARC-F定义的Sarkaryic女性的身体表现显着低于nonsarcopenic女性。的SARC-F提高了预测身体性能差的能力。结论：SARC-F问卷筛选肌肉减少症的有效性，与FNIH标准相比，是有限的。然而，由SARC-F问卷定义的肌肉减少症大大提高了患者临床特征预测身体表现不佳的预测值。(C)2017年AMDA -急性后和长期护理医学协会。
Objectives: Screening for sarcopenia in daily practice can be challenging. Our objective was to explore whether the SARC-F questionnaire is a valid screening tool for sarcopenia (defined by the Foundation for the National Institutes of Health [FNIH] criteria). Moreover, we evaluated the physical performance of older women according to the SARC-F questionnaire.Design: Cross-sectional study.Participants: Data from the Toulouse and Lyon EPIDemiologie de l'OSteoporose study (EPIDOS) on 3025 women living in the community (mean age: 80.5 +/- 3.9 years), without a previous history of hip fracture, were assessed.Measurements: The SARC-F self-report questionnaire score ranges from 0 to 10: a score >= 4 defines sarcopenia. The FNIH criteria uses handgrip strength (GS) and appendicular lean mass (ALM; assessed by DXA) divided by body mass index (BMI) to define sarcopenia. Outcome measures were the following performance-based tests: knee-extension strength, 6-m gait speed, and a repeated chair-stand test. The associations of sarcopenia with performance-based tests was examined using bootstrap multiple linear-regression models; adjusted R-2 determined the percentage variation for each outcome explained by the model.Results: Prevalence of sarcopenia was 16.7% (n = 504) according to the SARC-F questionnaire and 1.8% (n = 49) using the FNIH criteria. Sensibility and specificity of the SARC-F to diagnose sarcopenia (defined by FNIH criteria) were 34% and 85%, respectively. Sarcopenic women defined by SARC-F had significantly lower physical performance than nonsarcopenic women. The SARC-F improved the ability to predict poor physical performance.Conclusion: The validity of the SARC-F questionnaire to screen for sarcopenia, when compared with the FNIH criteria, was limited. However, sarcopenia defined by the SARC-F questionnaire substantially improved the predictive value of clinical characteristics of patients to predict poor physical performance. (C) 2017 AMDA - The Society for Post-Acute and Long-Term Care Medicine.