Capturing Human Perceptual and Cognitive Activities via Event-Related Potentials Measured with Candle-Like Dry Microneedle Electrodes
Capturing Human Perceptual and Cognitive Activities via Event-Related Potentials Measured with Candle-Like Dry Microneedle Electrodes
复制标题
DOI：
10.3390/mi11060556
复制
发表时间：
2020-05
期刊：
影响因子：
3.4
通讯作者：
Y. Yoshida;Takumi Kawana;Eiichi Hoshino;Yasuyo Minagawa;N. Miki
中科院分区：
文献类型：
--
作者：
Y. Yoshida;Takumi Kawana;Eiichi Hoshino;Yasuyo Minagawa;N. Miki
我们证明捕获事件相关电位（ERP）使用蜡烛状干微针电极（CME）。与传统的湿电极不同，CME甚至可以在没有任何皮肤准备的情况下从毛发区域记录脑电图（EEG）。在我们以前的研究中，我们实验验证了CME可以测量自发电位从毛枕区没有准备的信噪比一样好，传统的湿电极，需要皮肤准备。然而，这些结果是基于基于频率的信号，与噪声污染相比相对稳健，CME是否足够敏感以捕获更精细的信号仍不清楚。在这里，我们首先实验验证，CME可以提取ERPs一样好，传统的湿电极没有准备。在听觉oddball任务中，使用纯音，P300，这代表ERPs，提取与传统的湿电极的信噪比一样好。CME成功地捕获了感知活动。然后，我们试图用ERPs研究大脑的认知活动。在处理诸如/itta/、/itte/和/itta？/等听觉刺激中的元音和韵律时，在近红外光谱（NIRS）和脑磁图实验中观察到源自负责该过程的位置的偏侧性。我们同时测量事件相关电位与CME和近红外光谱在古怪的任务，使用三个词。偏侧出现在近红外光谱的10名参与者中的6名，虽然偏侧没有清楚地显示在结果中，这表明脑电图有一个有限的空间分辨率差。另一方面，使用不需要皮肤准备的CME成功捕获MMN和P300可以容易地适用于人类感知活动的实时应用。
We demonstrate capture of event-related potentials (ERPs) using candle-like dry microneedle electrodes (CMEs). CMEs can record an electroencephalogram (EEG) even from hairy areas without any skin preparation, unlike conventional wet electrodes. In our previous research, we experimentally verified that CMEs can measure the spontaneous potential of EEG from the hairy occipital region without preparation with a signal-to-noise ratio as good as that of the conventional wet electrodes which require skin preparation. However, these results were based on frequency-based signals, which are relatively robust compared to noise contamination, and whether CMEs are sufficiently sensitive to capture finer signals remained unclear. Here, we first experimentally verified that CMEs can extract ERPs as good as conventional wet electrodes without preparation. In the auditory oddball tasks using pure tones, P300, which represent ERPs, was extracted with a signal-to-noise ratio as good as that of conventional wet electrodes. CMEs successfully captured perceptual activities. Then, we attempted to investigate cerebral cognitive activity using ERPs. In processing the vowel and prosody in auditory stimuli such as /itta/, /itte/, and /itta?/, laterality was observed that originated from the locations responsible for the process in near-infrared spectroscopy (NIRS) and magnetoencephalography experiments. We simultaneously measured ERPs with CMEs and NIRS in the oddball tasks using the three words. Laterality appeared in NIRS for six of 10 participants, although laterality was not clearly shown in the results, suggesting that EEGs have a limitation of poor spatial resolution. On the other hand, successful capturing of MMN and P300 using CMEs that do not require skin preparation may be readily applicable for real-time applications of human perceptual activities.