Diabetes and diabetic retinopathy in a Mexican American population -: Proyecto VER
Diabetes and diabetic retinopathy in a Mexican American population -: Proyecto VER
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DOI：
10.2337/diacare.24.7.1204
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发表时间：
2001-07-01
期刊：
影响因子：
16.2
通讯作者：
Snyder, R
中科院分区：
文献类型：
--
作者：
West, SK;Klein, R;Snyder, R
目的：拉美裔人的糖尿病患病率可能高于高加索人，尽管关于糖尿病视网膜病变风险的差异存在争议。这项研究的目的是在一项基于人群的研究中确定糖尿病和糖尿病视网膜病变的患病率。研究设计和方法-Proyecto ver是亚利桑那州年龄大于或等于40岁的西班牙裔人口的随机样本。共有4774人(占合格样本的71.6%)完成了考试。糖尿病被定义为医生诊断或HbA(1c)值大于或等于7.0%的自我报告。糖尿病视网膜病变通过视野1、2和4的立体眼底照片进行评估。结果：西班牙裔社区(年龄大于或等于40岁)的糖尿病患病率为22%。糖尿病视网膜病变(DR)患病率为48%，中、重度非增殖性和增殖性视网膜病变占32%。DR随着糖尿病病程的延长和HBA(1c)水平的升高而增加。在没有糖尿病视网膜病变的个体样本中，类DR改变的患病率为15%，与高血压、收缩压或舒张压无关。结论--拉美裔人群中糖尿病的患病率很高，几乎是高加索人的两倍。糖尿病视网膜病变的患病率很高，但与高加索人群的报告相似。在新诊断的人群中，9%的中度到重度视网膜病变的患病率表明，努力改善拉美裔糖尿病的诊断和治疗可能是必要的。
OBJECTIVES - The prevalence rate of diabetes is probably higher in Hispanics than in Caucasians, although there is controversy about differences in the risk of diabetic retinopathy. The purpose of the study is to determine the prevalence rates of diabetes and diabetic retinopathy in a population-based study of Hispanics aged greater than or equal to 40 years.RESEARCH DESIGN AND METHODS - Proyecto VER is a random sample of Hispanic populations aged greater than or equal to 40 years in Arizona. A total of 4,774 individuals (71.6% of the eligible sample) completed the examinations. Diabetes was defined as self-report of a physician diagnosis or HbA(1c) value of greater than or equal to7.0%. Diabetic retinopathy was assessed on stereo fundus photographs of fields 1, 2, and 4.RESULTS - The prevalence rate of diabetes in the Hispanic community (individuals greater than or equal to 40 years of age) was 22%. The prevalence rate of diabetic retinopathy (DR) was 48%; 32% had moderate to severe nonproliferative and proliferative retinopathy. DR increased with increasing duration of diabetes and increasing level of HbA(1c). The prevalence rate of DR-like changes in the sample of individuals without diabetic retinopathy was 15% and was not associated with hypertension, systolic blood pressure, or diastolic blood pressure.CONCLUSIONS - The prevalence rate of diabetes in this population of Hispanics is high, almost twice that of Caucasians. The prevalence rate of DR is high but similar to reports in a Caucasian population. The prevalence rate of 9% moderate to severe retinopathy in the newly diagnosed group suggests that efforts to improve detection and treatment of diabetes in Hispanics may be warranted.