Individualizing PSA Monitoring Among Older Prostate Cancer Survivors.
Individualizing PSA Monitoring Among Older Prostate Cancer Survivors.
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对老年前列腺癌幸存者进行个体化 PSA 监测。
DOI：
10.1007/s11606-018-4334-9
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发表时间：
2018
影响因子：
5.7
通讯作者：
Walter,LouiseC
中科院分区：
文献类型：
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作者：
Shi,Ying;Fung,KathyZ;JohnBoscardin,W;Ngo,Sarah;Freedland,StephenJ;Wong,MelisaL;Walter,LouiseC
方法我们利用退伍军人事务部癌症登记中心对13,397名65岁或以上的男性进行了纵向队列研究，这些人在1/1/03至12/31/08年1月1日至12月31日期间新诊断为临床局限性前列腺癌，接受了最初的根治性前列腺癌切除术或放射治疗，并在治疗后至少一年内没有生化复发。使用国家退伍军人管理局和医疗保险数据，所有男性在治疗一周年后进行了4年的跟踪调查。我们排除了那些没有退伍军人保险或联邦医疗保险作为主要保险的男性，以及那些在研究期间参加联邦医疗保险HMO的男性，因为他们缺乏确定合并症或PSA监测的索赔。
METHODSWe used the VA Central Cancer Registry to conduct a longitudinal cohort study of 13,397 men age 65 or older who were newly diagnosed with clinically localized prostate cancer between 1/1/03 and 12/31/08, received initial curative-intent radical prostatectomy or radiation, and survived without biochemical recurrence for at least 1 year after treatment. All men were followed for 4 years after their 1-year treatment anniversary date using national VA and Medicare data. We excluded men who did not have VA or Medicare as their primary insurance and those enrolled in Medicare HMO during the study period because they lacked claims to determine comorbidities or PSA monitoring.