Epidemiology of vestibular vertigo - A neurotologic survey of the general population
Epidemiology of vestibular vertigo - A neurotologic survey of the general population
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DOI：
10.1212/01.wnl.0000175987.59991.3d
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发表时间：
2005-09-27
期刊：
影响因子：
9.9
通讯作者：
Lempert, T
中科院分区：
文献类型：
--
作者：
Neuhauser, HK;von Brevern, M;Lempert, T
目的：本研究的目的是确定前庭性眩晕在普通人群中的患病率和发病率，并描述其临床特征和相关因素。2003年德国全国电话健康访问调查中的全国性改良随机数字拨号抽样（应答率52%），对4，869名参与者进行随机抽样，筛查中度或重度头晕或眩晕，然后通过试点和验证进行详细的神经耳病学访谈（n = 1，003，应答率87%）。前庭性眩晕的诊断标准是旋转性眩晕、位置性眩晕或伴有恶心、眩晕或失衡的复发性头晕。结果：61例前庭性眩晕的终生患病率为7.8%，1年患病率为5.2%，发病率为1.5%。在80%的受影响的人中，眩晕导致了医疗咨询，日常活动中断或病假。在单因素分析中，女性、年龄、低教育水平和各种共病情况，包括耳鸣、抑郁症和几种心血管疾病和危险因素，与过去一年的前庭眩晕相关。在多变量分析中，只有女性性别，自我报告的抑郁症，耳鸣，高血压，血脂异常有独立的影响前庭vertile.Conclusions：前庭性眩晕是常见的，在一般人群中，影响超过5%的成年人在1年。前庭症状在人群水平上的频率和卫生保健影响被低估了。
Objective: The purpose of this study was to determine the prevalence and incidence of vestibular vertigo in the general population and to describe its clinical characteristics and associated factors.Methods: The neurotologic survey had a two-stage general population sampling design: nationwide modified random digit dialing sampling for participation in the German National Telephone Health Interview Survey 2003 ( response rate 52%) with screening of a random sample of 4,869 participants for moderate or severe dizziness or vertigo, followed by detailed neurotologic interviews developed through piloting and validation (n = 1,003, response rate 87%). Diagnostic criteria for vestibular vertigo were rotational vertigo, positional vertigo, or recurrent dizziness with nausea and oscillopsia or imbalance. Vestibular vertigo was detected by our interview with a specificity of 94% and a sensitivity of 88% in a concurrent validation study using neurotology clinic diagnoses as an accepted standard (n = 61).Results: The lifetime prevalence of vestibular vertigo was 7.8%, the 1-year prevalence was 5.2%, and the incidence was 1.5%. In 80% of affected individuals, vertigo resulted in a medical consultation, interruption of daily activities, or sick leave. Female sex, age, lower educational level, and various comorbid conditions, including tinnitus, depression, and several cardiovascular diseases and risk factors, were associated with vestibular vertigo in the past year in univariate analysis. In multivariable analysis, only female sex, self-reported depression, tinnitus, hypertension, and dyslipidemia had an independent effect on vestibular vertigo.Conclusions: Vestibular vertigo is common in the general population, affecting more than 5% of adults in 1 year. The frequency and health care impact of vestibular symptoms at the population level have been underestimated.