The electrical activity of regenerating nerves in the cat

The electrical activity of regenerating nerves in the cat
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DOI:
10.1152/jn.1944.7.2.103
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发表时间:
1944-03-01
影响因子:
2.5
通讯作者:
Hinsey, JC
Hinsey, JC
中科院分区:
医学3区
文献类型:
--
作者:
Berry, CM;Grundfest, H;Hinsey, JC

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动作电位和组织学准备。在初次缝合后的466天内取自再生的腓骨神经、胫骨神经和隐神经。在第17天,高阈值电刺激在远端残端激发传导小于1 mps的小动作电位。当脉冲通过逐渐移动电极追踪到中心残端时,最大传导速度突然增加,阈值相应降低。远端最大传导速度和最大纤维直径随再生时间的延长而缓慢增加,即使在466天也不完全恢复。再生神经的最大传导速度与最大纤维直径的关系近似。线性的。
Action potentials and histological prepns. were taken from regenerating peroneal, tibial, and saphenous nerves at various intervals up to 466 days following primary suture. At 17 days, small action potentials conducting at less than 1 mps were elicited in the distal stump by high threshold electrical stimuli. When the impulses were traced into the central stump by progressively shifting the electrodes, the maximum conduction velocities increased abruptly with a corresponding decrease in threshold. Distally, both the maximum conduction velocity and the maximum fiber diam. increased slowly with the time of regeneration so that the return was incomplete even at 466 days. The relationship between maximum conduction velocity and maximum fiber diam. of regenerating nerves was approx. linear.