Developing more effective seizure therapies requires more selective drugs.
Developing more effective seizure therapies requires more selective drugs.
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开发更有效的癫痫治疗方法需要更具选择性的药物。
DOI：
10.1113/jp278229
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发表时间：
2019
期刊：
影响因子：
--
通讯作者：
Brickley S
中科院分区：
文献类型：
--
作者：
Brickley S
探讨SB 2 sb亚单位含有GABA SB A sb受体在确定Dravet综合征小鼠模型癫痫发作严重程度中的重要性。然而，这种癫痫发作表型的严重程度似乎受到疾病修饰基因的显著影响，包括GABA SB A SB受体的SB 2 SB亚基。[摘自文章]
explore the importance of SB 2 sb subunit-containing GABA SB A sb receptors in determining seizure severity in a mouse model of Dravet syndrome. The severity of this seizure phenotype, however, seems to be dramatically influenced by disease modifier genes, including the SB 2 sb subunit of the GABA SB A sb receptor.[Extracted from the article]