From Neurogenetic Studies in the Fly Brain to a Concept in Circadian Biology

From Neurogenetic Studies in the Fly Brain to a Concept in Circadian Biology
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DOI:
10.3109/01677063.2014.905556
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发表时间:
2014-09-01
影响因子:
1.9
通讯作者:
Helfrich-Foerster, Charlotte
Helfrich-Foerster, Charlotte
中科院分区:
医学4区
文献类型:
--
作者:
Helfrich-Foerster, Charlotte

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这篇论文是献给卡尔·弗里德里希·菲施巴赫的,他一直和我分享对苍蝇大脑功能的兴趣,特别是它的视叶。他一直陪伴着我走上科学研究的第一步。这篇论文讲述了我们第一次共同尝试在苍蝇大脑中定位生物钟的故事,最终帮助描述了生物钟的双振荡器原理,该原理似乎远远超出了苍蝇的生物钟系统。我希望卡尔-弗里德里希会把这个故事当作对他慷慨支持自己实验室以外的年轻科学家的赞扬,即使没有一篇普通论文的奖励。
This paper is dedicated to Karl-Friedrich Fischbach, who has always shared with me the interest in the function of the fly brain, especially that of its optic lobes. He has accompanied me during my first steps in scientific research. The paper tells the story how our first common attempts to localize the circadian clock in the fly brain finally helped in phrasing the two-oscillator principle of circadian clocks that seems to be valid far beyond the fly circadian system. I hope that Karl-Friedrich will take this story as praise for his generosity in supporting younger scientists outside his own lab, even without the reward of a common paper.