Impulse Noise Injury Model
Impulse Noise Injury Model
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DOI：
10.7205/milmed-d-15-00139
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发表时间：
2016-05-01
影响因子：
1.2
通讯作者：
Ryan, Allen F.
中科院分区：
文献类型：
--
作者：
Chan, Philemon;Ho, Kevin;Ryan, Allen F.
目的：新的Auditory 4.0模型已开发用于评估未受保护耳朵暴露于脉冲噪声的听觉结果，表示为暂时性阈值偏移（TTS）和永久性阈值偏移（PTS），包括预测TTS恢复。方法：听觉4.0是一个经验模型，从实验室脉冲噪声暴露的龙猫收集的测试数据构建。损伤结果被定义为TTS和PTS，Auditory4.0提供了TTS和PTS剂量反应曲线的全部范围，其中风险因子由A加权声音暴露水平构建。大型武器噪声暴露的人类数据也被用来指导恢复模型的开发。结果：在数据的指导下，将28-dBA偏移应用于剂量-反应曲线，以解释从龙猫到人类的缩放。来自步枪噪声测试的历史数据用于验证剂量-反应曲线。新的灰鼠测试进行收集恢复数据，构建TTS恢复模型。结论：Auditory 4.0是迄今为止唯一已知的提供完整TTS和PTS剂量-反应曲线的模型，包括TTS恢复模型。该模型与历史数据吻合良好。
Objectives: The new Auditory 4.0 model has been developed for the assessment of auditory outcomes, expressed as temporary threshold shift (TTS) and permanent threshold shift (PTS), from exposures to impulse noise for unprotected ears, including the prediction of TTS recovery. Methods: Auditory 4.0 is an empirical model, constructed from test data collected from chinchillas exposed to impulse noise in the laboratory. Injury outcomes are defined as TTS and PTS, and Auditory 4.0 provides the full range of TTS and PTS dose-response curves with the risk factor constructed from A-weighted sound exposure level. Human data from large weapons noise exposure was also used to guide the development of the recovery model. Results: Guided by data, a 28-dBA shift was applied to the dose-response curves to account for the scaling from chinchillas to humans. Historical data from rifle noise tests were used to validate the dose-response curves. New chinchilla tests were performed to collect recovery data to construct the TTS recovery model. Conclusions: Auditory 4.0 is the only model known to date that provides the full TTS and PTS dose-response curves, including a TTS recovery model. The model shows good agreement with historical data.