Pentamidine Congeners 1: Synthesis of Cis- and Trans-Butamidine Analogues As Anti-Pneumocystis carinii Pneumonia Agents.
Pentamidine Congeners 1: Synthesis of Cis- and Trans-Butamidine Analogues As Anti-Pneumocystis carinii Pneumonia Agents.
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喷他脒同源物 1：作为抗卡氏肺囊虫肺炎药物的顺式和反式丁脒类似物的合成。
DOI：
10.1016/s0960-894x(00)80302-9
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发表时间：
1993
影响因子：
2.7
通讯作者：
Tidwell,RichardR
中科院分区：
文献类型：
--
作者：
Donkor,IsaacO;Jones,SusanK;Tidwell,RichardR
Butamidine analogues possessing unsaturation in the ether bridge between the bisamidinophenyl or bisimidazolinophenyl functionalities have been synthesized as semirigid congeners of pentamidine. These compounds demonstrated good anti-P. cariniipneumonia activity in a rat model of the disease.
