Differential expression of genes coding for ribosomal proteins in different human tissues
Differential expression of genes coding for ribosomal proteins in different human tissues
复制标题
DOI：
10.1093/bioinformatics/17.12.1152
复制
发表时间：
2001-12-01
期刊：
影响因子：
5.8
通讯作者：
Danieli, GA
中科院分区：
文献类型：
--
作者：
Bortoluzzi, S;d'Alessi, F;Danieli, GA
动机：为了分析核糖体蛋白基因的表达，对一个大的基因表达数据集（脑，肝，骨骼肌，卵巢，视网膜和子宫）进行计算和统计研究。此外，当比较89个核糖体蛋白基因在6种不同组织中的表达水平时，13个基因在组织间出现差异表达。
Motivation: To perform a computational and statistical study on a large set of gene expression data pertaining six adult human tissues (brain, liver, skeletal muscle, ovary, retina and uterus) for analyzing the expression of ribosomal protein genes.Results: Unexpectedly, in each of the considered tissues large variations in the expression of ribosomal protein genes were observed. Moreover, when comparing the expression levels of 89 ribosomal protein genes in six different tissues, 13 genes appeared differentially expressed among tissues.