Aging and wound healing
Aging and wound healing
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DOI：
10.1007/s00268-003-7397-6
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发表时间：
2004-03-01
影响因子：
2.6
通讯作者：
DiPietro, A
中科院分区：
文献类型：
--
作者：
Gosain, A;Luisa, MD;DiPietro, A
老年人创面愈合受损是一个重大的临床和经济问题。随着老龄化人口的数量和比例的增加，了解年龄相关损伤在康复中潜在的机制的重要性增加了。正常皮肤随着年龄的增长表现出特征性的变化，这对伤口的愈合有影响。此外，老年人的伤口愈合过程也会发生变化。虽然在历史上，老年人的康复被认为是有缺陷的，但现在人们一致认为，老年人的康复是延迟的，但最终结果在质量上与年轻受试者相似。
Impaired wound healing in the elderly presents a major clinical and economic problem. With the aging population growing in both number and percentage, the importance of understanding the mechanisms underlying age-related impairments in healing is increased. Normal skin exhibits characteristic changes with age that have implications for wound healing. Additionally, the process of wound healing is altered in aged individuals. Although historically healing in the aged was considered defective, there is now consensus that healing in the elderly is delayed but the final result is qualitatively similar to that in young subjects.