Mixed-conducting particulate composites for soft electronics
Mixed-conducting particulate composites for soft electronics
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DOI：
10.1126/sciadv.aaz6767
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发表时间：
2020-04-01
期刊：
影响因子：
13.6
通讯作者：
Khodagholy, Dion
中科院分区：
文献类型：
--
作者：
Jastrzebska-Perfect, Patricia;Spyropoulos, George D.;Khodagholy, Dion
生物电子设备应以最佳方式将柔软的、生物相容性的组织界面与本地先进的信号处理能力相结合。在这里，我们介绍了一种有机混合导电颗粒复合材料（MCP），它可以通过改变颗粒尺寸和密度来形成功能电子元件。我们创建了基于 MCP 的高性能各向异性薄膜、可独立寻址的晶体管、电阻器和二极管，它们无图案、可扩展且生物相容。 MCP 能够在软电子和刚性电子器件之间实现轻松有效的电子连接，从而能够以自由移动的啮齿动物以及通过头骨上的小开口从人脑表面的单个神经元的分辨率记录神经生理学数据。我们还通过直接将 MCP 与人体皮肤连接来无创地获取高时空分辨率的电生理信号。 MCP 提供单一材料解决方案，以促进能够安全采集、传输和处理复杂生物信号的生物电子设备的开发。
Bioelectronic devices should optimally merge a soft, biocompatible tissue interface with capacity for local, advanced signal processing. Here, we introduce an organic mixed-conducting particulate composite material (MCP) that can form functional electronic components by varying particle size and density. We created MCP-based high-performance anisotropic films, independently addressable transistors, resistors, and diodes that are pattern free, scalable, and biocompatible. MCP enabled facile and effective electronic bonding between soft and rigid electronics, permitting recording of neurophysiological data at the resolution of individual neurons from freely moving rodents and from the surface of the human brain through a small opening in the skull. We also noninvasively acquired high-spatiotemporal resolution electrophysiological signals by directly interfacing MCP with human skin. MCP provides a single-material solution to facilitate development of bioelectronic devices that can safely acquire, transmit, and process complex biological signals.