Polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, and coplanar polychlorinated biphenyls in breast milk from two cities in Ukraine
Polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, and coplanar polychlorinated biphenyls in breast milk from two cities in Ukraine
复制标题
DOI：
10.1080/009841099157331
复制
发表时间：
1999-10-15
影响因子：
2.6
通讯作者：
Little, RE
中科院分区：
文献类型：
--
作者：
Gladen, BC;Schecter, AJ;Little, RE
乌克兰据称遭受了严重的环境污染，但几乎没有信息可以评估对人类可能产生的影响。为了帮助弥补信息的缺乏，有必要调查乌克兰人体内某些多氯二苯并二恶英 (PCDD)、多氯二苯并呋喃 (PCDF) 或共面多氯联苯 (PCB) 的含量是否升高。母乳样本取自基辅市和第聂伯罗捷尔任斯克市的 200 名妇女；基辅是首都，第聂伯罗捷尔任斯克是一座高度工业化的城市。样品按城市和年龄分为四个池，并分析了 7 种 PCDD、10 种 PCDF 和 2 种共面 PCB（126 和 169）。测得的 PCDD 总量（以毒性当量表示）范围为 5.1 至 7.6 pg/g 脂质； PCDF 的含量为 3.6 至 5.2，PCB 的含量为 11 至 18 pg/g 脂质。两个城市的结果相似；老年女性的浓度略高于年轻女性。在乌克兰发现的这些化合物的水平与欧洲和亚洲国家最近的其他研究中发现的水平相似或更低。
Substantial environmental pollution has been alleged in Ukraine, but little information is available to allow an assessment of the possible impact on humans. To help remedy this lack of information, it was of interest to investigate whether certain polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), or coplanar polychlorinated biphenyls (PCBs) were elevated in people from Ukraine. Samples of breast milk were obtained from 200 women from the cities of Kyiv and Dniprodzerzhinsk; Kyiv is the capital and Dniprodzerzhinsk is a highly industrialized city. The samples were combined into four pools by city and age, and analyzed for 7 PCDDs, 10 PCDFs, and 2 coplanar PCBs (126 and 169). The total of the measured PCDDs, expressed as toxic equivalents, ranged from 5.1 to 7.6 pg/g lipid; for PCDFs from 3.6 to 5.2, and for PCBs from 11 to 18 pg/g lipid. Results from the two cities were similar; older women had slightly higher concentrations than did younger women. Levels of these compounds seen in Ukraine were similar to or lower than those seen in other recent studies from European and Asian countries.