Crossing the quality chasm for Clostridium difficile infection prevention.
Crossing the quality chasm for Clostridium difficile infection prevention.
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跨越艰难梭菌感染预防的质量鸿沟。
DOI：
10.1136/bmjqs-2015-004344
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发表时间：
2015
影响因子：
5.4
通讯作者：
Perencevich,Eli
中科院分区：
文献类型：
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作者：
Safdar,Nasia;Perencevich,Eli
艰难梭菌是一种形成孢子的有机体，它导致了多达25%的卫生保健相关腹泻病例。1-4在许多发达国家，艰难梭菌感染（CDI）现在是最重要的卫生保健相关感染（HAI），这表明迫切需要有效遏制策略。5 .最近关于抗菌剂管理倡议和CDI预防“捆绑包”影响的研究报告显示，CDI率有不同程度的降低。6-10例如，最近的一项荟萃分析发现，实施抗微生物药物管理规划与CDI率降低50%有关，特别是如果它采用限制性而非说服性政策。随着其他类型的HAI，如中央静脉（CL）相关血流感染和导尿管相关尿路感染的下降，许多医疗机构采用了类似的方法来减少推荐做法和捆绑干预措施
Clostridium difficile, a spore-forming organism, causes as many as 25% of cases of healthcare-associated diarrhoea. 1–4 In many developed countries, C. difficile infection (CDI) is now the most important healthcare-associated infection (HAI), suggesting an urgent need of strategies for effective containment. 5 Recent studies on the impact of antimicrobial stewardship initiatives and CDI prevention ‘bundles’ have reported variable reductions in CDI rates. 6–10 For example, a recent meta-analysis found that implementing an antimicrobial stewardship programme was associated with a 50% reduction in CDI rates, particularly if it utilised restrictive over persuasive policies. 11 Following declines in other types of HAI such as central line (CL)-associated bloodstream infection and catheter-associated urinary tract infection with the use of a checklist of recommended practices and bundled interventions, many healthcare institutions have adopted a similar approach to reducing