Clan mentality: evidence that the medial prefrontal cortex responds to close others.
Clan mentality: evidence that the medial prefrontal cortex responds to close others.
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DOI：
10.1523/jneurosci.2180-10.2010
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发表时间：
2010-10-13
期刊：
影响因子：
--
通讯作者：
Buckner RL
中科院分区：
文献类型：
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作者：
Krienen FM;Tu PC;Buckner RL
亲属关系、友谊联盟和对他人信仰的看法指导着社会互动，是有凝聚力的群体行为的核心。在某些情况下，当对与自己观点相似的其他人做出推断时，涉及额叶中线区域的大脑系统会增加活动（相似性）。一个突出的假设是，这些区域通过根据自己的经验模拟他人的观点来促进社会认知。另一种方法是，某些区域处理人与自己的社会相关性（亲近度），并有助于评估，类似于控制行为方法反应的信号。通过四项功能磁共振成像实验 (n=98) 探索了这些替代方案。实验1通过让参与者做出个人判断来定位头侧前扣带皮层和前内侧前额叶皮层的目标中线区域。在实验 2 中，使用参与者的实际朋友和未知的其他人来交叉两个维度（相似性、亲密性）。无论朋友是否与参与者有相似的观点，对自己和朋友做出判断都会导致相对于未知其他人的中线反应增加。实验 3 表明，即使不包括亲密的其他人，相似性也不是一个因素。实验4直接对比了两个极端：参与者对相似的、未知的他人和不相似的朋友做出推断。对亲密他人的判断再次增加了额叶中线的大胆反应。这些结果鼓励进一步探索这样的想法：与边缘回路相连的额叶系统有助于评估社会环境中的相关性或个人意义。
Kinship, friendship alliances, and perceptions of others’ beliefs guide social interactions and are central to cohesive group behavior. Under certain conditions, brain systems that involve regions along the frontal midline increase activity when inferences are drawn about others who share a similar view to one’s own (Similarity). A prominent hypothesis is that these regions contribute to social cognition by simulating the other person’s perspective based on one’s own experience. An alternative is that certain regions process the social relevance of the person (Closeness) to oneself and contribute to the assessment akin to signals that govern behavioral approach responses. These alternatives were explored across four fMRI experiments (n=98). Experiment 1 localized the target midline regions in rostral anterior cingulate cortex and anterior medial prefrontal cortex by having participants make personal judgments. The two dimensions (Similarity, Closeness) were crossed in Experiment 2 using actual friends of the participant and unknown others. Making judgments about oneself and friends resulted in increased midline response relative to unknown others regardless of whether the friends shared similar views as the participant. Experiment 3 revealed that similarity was not a factor even when close others were not included. Experiment 4 directly contrasted two extremes: participants made inferences about similar, unknown others and dissimilar friends. Judgments about the close others again increased BOLD response along the frontal midline. These results encourage further exploration of the idea that frontal systems linked with limbic circuits facilitate assessment of the relevance or personal significance in social contexts.