Speech-evoked cognitive P300 potentials in cochlear implant recipients.
Speech-evoked cognitive P300 potentials in cochlear implant recipients.
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人工耳蜗植入者的言语诱发认知 P300 电位。
DOI：
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发表时间：
1995
期刊：
影响因子：
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通讯作者：
R. Wiet
中科院分区：
文献类型：
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作者：
A. Micco;N. Kraus;D. Koch;T. McGee;T. Carrell;Anu Sharma;T. Nicol;R. Wiet
言语刺激诱发耳蜗植入成功者的认知P300诱发电位，P300形态与听力正常者显著相似。P300是通过对9名“良好”的人工耳蜗使用者和9名年龄匹配的正常听力受试者（34-81岁）采用一种怪异范式呈现的合成语音对/da/和/di/引发的。P300振幅和潜伏期在两组间无显著差异。此外，两组的N1和P2电位出现相似的潜伏期，尽管人工耳蜗使用者的N1振幅明显较小。一名“较差”的人工耳蜗使用者没有P300。结果表明，P300可作为评估人工耳蜗受者听觉加工认知方面的有用工具，并有助于评估人工耳蜗植入的成功。
The cognitive P300 evoked potential was elicited by speech stimuli in successful cochlear implant recipients, and the resulting P300 morphology was remarkably similar to that of normal-hearing individuals. The P300 was elicited by the synthesized speech pair/da/and/di/ presented using an oddball paradigm to nine "good" Nucleus cochlear implant users and nine age-matched normal-hearing subjects (34-81 yr old). There were no significant differences in P300 amplitude and latency between the two groups. Moreover, the N1 and P2 potentials occurred at similar latencies in the two groups, although the N1 amplitude was significantly smaller in the cochlear implant users. The P300 was absent in one "poor" cochlear implant user. The results suggest that the P300 may serve as a useful tool for evaluating the cognitive aspects of auditory processing in cochlear implant recipients, and that it may aid in assessing the success of cochlear implantation.