Chlamydial and gonococcal reinfection among men: a systematic review of data to evaluate the nee for retesting
Chlamydial and gonococcal reinfection among men: a systematic review of data to evaluate the nee for retesting
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DOI：
10.1136/sti.2006.024059
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发表时间：
2007-07-01
影响因子：
3.6
通讯作者：
Klausner, Jeffrey D.
中科院分区：
文献类型：
--
作者：
Fung, Monica;Scott, Katherine C.;Klausner, Jeffrey D.
本研究旨在系统地回顾和描述男性衣原体和淋病再感染的证据，并评估男性重新检测建议的必要性。检索1995年1月至2006年10月的PubMed和STI会议摘要书籍，以确定使用衣原体和淋病核酸扩增试验或淋病培养对男性衣原体和淋病再感染的研究。研究被分类为使用主动或被动随访方法。计算每项研究中男性衣原体和淋球菌再感染的比例，并报告总结中位数。在男性中，衣原体重复感染的中位再感染概率为11.3%。男性反复淋病感染的再感染概率中位数为7.0%。积极随访的研究显示，男性衣原体和淋病再感染率中等，中位数分别为10.9%和7.0%。被动随访的研究中，男性衣原体和淋病再感染的比例较高，中位数分别为17.4%和8.5%。男子中衣原体和淋病再感染的比例与妇女中的比例相当。男性再次感染与既往性传播疾病史和年龄较轻密切相关，与危险性行为的相关性不一致。大量的衣原体和淋病的重复感染率在男性中发现与女性的那些。考虑到再感染率高，建议对男性进行重新检测是适当的。为了优化复检指南，建议进一步研究以确定有效的复检方法并建立与男性再感染相关的因素。
This study aimed to systematically review and describe the evidence on chlamydia and gonorrhoea reinfection among men, and to evaluate the need for retesting recommendations in men. PubMed and STI conference abstract books from January 1995 to October 2006 were searched to identify studies on chlamydia and gonorrhoea reinfection among men using chlamydia and gonorrhoea nucleic acid amplification tests or gonorrhoea culture. Studies were categorised as using either active or passive follow-up methods. The proportions of chlamydial and gonococcal reinfection among men were calculated for each study and summary medians were reported. Repeat chlamydia infection among men had a median reinfection probability of 11.3%. Repeat gonorrhoea infection among men had a median reinfection probability of 7.0%. Studies with active follow-up had moderate rates of chlamydia and gonorrhoea reinfection among men, with respective medians of 10.9% and 7.0%. Studies with passive follow-up had higher proportions of both chlamydia and gonorrhoea reinfections among men, with respective medians of 17.4% and 8.5%. Proportions of chlamydia and gonorrhoea reinfection among men were comparable with those among women. Reinfection among men was strongly associated with previous history of sexually transmitted diseases and younger age, and inconsistently associated with risky sexual behaviour. Substantial repeat chlamydia and gonorrhoea infection rates were found in men comparable with those in women. Retesting recommendations in men are appropriate, given the high rate of reinfection. To optimise retesting guidelines, further research to determine effective retesting methods and establish factors associated with reinfection among men is suggested.