Auditory Target Detection Enhances Visual Processing and Hippocampal Functional Connectivity.
Auditory Target Detection Enhances Visual Processing and Hippocampal Functional Connectivity.
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DOI：
10.3389/fpsyg.2022.891682
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发表时间：
2022
影响因子：
3.8
通讯作者：
Swallow, Khena M
中科院分区：
文献类型：
--
作者：
Moyal, Roy;Turker, Hamid B;Luh, Wen-Ming;Swallow, Khena M
虽然将一个人的注意力分散在两个输入流中通常会影响性能，但检测到与行为相关的刺激有时可以增强对同时呈现的无关信息的编码。先前的研究表明，选择这种类型的东西会增强视觉皮质活动和对同时出现的项目的记忆。一个重要的悬而未决的问题是，这种影响是否反映在视觉区域和海马体的加工质量和功能连接上。在这项功能磁共振研究中，参与者被要求记住一系列自然图像，并只有在听到预定义的目标音(400或1200赫兹，平衡)时才按下按钮。图像可以用目标色调呈现，可以用干扰色调呈现，也可以不用色调呈现。听觉目标检测增加了整个腹侧视觉皮质的活动，但降低了海马区的活动。随着听觉目标的出现，腹侧视觉皮质和海马体之间的功能连接也得到了增强。在目标音调试验中，图像类别的多体素模式分类比在梭状回和海马旁回的目标音调试验和无音调试验中更准确。这种影响在视觉皮层簇中更强，其活动与海马体在目标音调上的相关性比在干扰音调试验中更强。与皮质下去甲肾上腺素影响在注意增强效应中起作用的说法一致，听觉目标检测也引起蓝斑活动和时相瞳孔反应的增加。这些发现概述了一个皮质和皮质下区域的网络，这些区域参与选择和处理在行为相关时刻呈现的信息。
Though dividing one’s attention between two input streams typically impairs performance, detecting a behaviorally relevant stimulus can sometimes enhance the encoding of unrelated information presented at the same time. Previous research has shown that selection of this kind boosts visual cortical activity and memory for concurrent items. An important unanswered question is whether such effects are reflected in processing quality and functional connectivity in visual regions and in the hippocampus. In this fMRI study, participants were asked to memorize a stream of naturalistic images and press a button only when they heard a predefined target tone (400 or 1,200 Hz, counterbalanced). Images could be presented with a target tone, with a distractor tone, or without a tone. Auditory target detection increased activity throughout the ventral visual cortex but lowered it in the hippocampus. Enhancements in functional connectivity between the ventral visual cortex and the hippocampus were also observed following auditory targets. Multi-voxel pattern classification of image category was more accurate on target tone trials than on distractor and no tone trials in the fusiform gyrus and parahippocampal gyrus. This effect was stronger in visual cortical clusters whose activity was more correlated with the hippocampus on target tone than on distractor tone trials. In agreement with accounts suggesting that subcortical noradrenergic influences play a role in the attentional boost effect, auditory target detection also caused an increase in locus coeruleus activity and phasic pupil responses. These findings outline a network of cortical and subcortical regions that are involved in the selection and processing of information presented at behaviorally relevant moments.