Oxidative Generation of α-Radicals of Carbonyl Compounds from the α-Stannyl Derivatives and Their Reactions with Electron-Rich Olefins
Oxidative Generation of α-Radicals of Carbonyl Compounds from the α-Stannyl Derivatives and Their Reactions with Electron-Rich Olefins
复制标题
α-甲锡烷基衍生物氧化生成羰基化合物的α-自由基及其与富电子烯烃的反应
DOI：
10.1246/bcsj.68.322
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发表时间：
1995
影响因子：
4
通讯作者：
K. Narasaka*
中科院分区：
文献类型：
--
作者：
Y. Kohno;K. Narasaka*
α-三丁基辛烷酸酯与己腈酸四丁基铵（IV）氧化，通过消除锡离子产生α-自由基。由此形成的自由基与各种富电子的烯烃化合物，如硅烯醇醚反应，生成收率高的加成产物。该方法正式实现了烷酸酯和酮类之间的选择性交叉偶联。
The oxidation of α-tributylstannyl alkanoates with tetrabutylammonium hexanitratocerate(IV) generates α-radicals of the alkanoates by eliminating the stannylium ion. The thus-formed radicals react with various electron-rich olefinic compounds, such as silyl enol ethers, giving addition products in good yield. This method formally achieves selective cross coupling between alkanoates and ketones.