Cytokinesis mechanics and mechanosensing.
Cytokinesis mechanics and mechanosensing.
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细胞分裂力学和机械传感。
DOI：
10.1002/cm.21045
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
Robinson,DouglasN
中科院分区：
文献类型：
--
作者：
West-Foyle,Hoku;Robinson,DouglasN
细胞分裂形状的变化是通过三个模块的接口发生的，即细胞力学、肌球蛋白 II 介导的收缩应力产生和传感，以及调节蛋白的控制系统，这些模块共同确保了灵活性和鲁棒性。然后，这个集成系统定义了成功胞质分裂的典型形状变化，这种变化发生在各种机械环境和环境条件下。 © 2012 Wiley 期刊公司。
Cytokinesis shape change occurs through the interfacing of three modules, cell mechanics, myosin II‐mediated contractile stress generation and sensing, and a control system of regulatory proteins, which together ensure flexibility and robustness. This integrated system then defines the stereotypical shape changes of successful cytokinesis, which occurs under a diversity of mechanical contexts and environmental conditions. © 2012 Wiley Periodicals, Inc.