GeneMANIA: Fast gene network construction and function prediction for Cytoscape.
GeneMANIA: Fast gene network construction and function prediction for Cytoscape.
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DOI：
10.12688/f1000research.4572.1
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发表时间：
2014-01-01
期刊：
影响因子：
--
通讯作者：
Morris, Quaid
中科院分区：
文献类型：
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作者：
Montojo, Jason;Zuberi, Khalid;Morris, Quaid
GeneMANIA Cytoscape 应用程序使用户能够从基因列表构建复合基因-基因功能交互网络。生成的网络包括与原始列表最相关的基因以及来自基因本体的功能注释。边缘注释有有关交互所源自的出版物或数据源的详细信息。该应用程序利用了 GeneMANIA 的 1800 多个网络数据库，其中包含 8 种生物的 5 亿多个交互：拟南芥、线虫、黑腹果蝇、雷里奥、智人、小家鼠、挪威野生动物和酿酒酵母。用户还可以导入自己的生物体、网络和表达谱。该应用程序与 Cytoscape 版本 2 和 3 兼容。
The GeneMANIA Cytoscape app enables users to construct a composite gene-gene functional interaction network from a gene list. The resulting network includes the genes most related to the original list, and functional annotations from Gene Ontology. The edges are annotated with details about the publication or data source the interactions were derived from. The app leverages GeneMANIA's database of 1800+ networks, containing over 500 million interactions spanning 8 organisms: A. thaliana, C. elegans, D. melanogaster, D. rerio, H. sapiens, M. musculus, R. norvegicus, and S. cerevisiae. Users may also import their own organisms, networks, and expression profiles. The app is compatible with Cytoscape versions 2 and 3.