Epidemiology of cerebral venous sinus thrombosis and cerebral venous sinus thrombosis with thrombocytopenia in the United States, 2018 and 2019.
Epidemiology of cerebral venous sinus thrombosis and cerebral venous sinus thrombosis with thrombocytopenia in the United States, 2018 and 2019.
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在2018年和2019年，脑静脉窦性血栓形成和血小板减少症的脑静脉窦性血栓形成的流行病学。
DOI：
10.1002/rth2.12682
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发表时间：
2022-03
影响因子：
4.6
通讯作者：
Schieve LA
中科院分区：
文献类型：
--
作者：
Payne AB;Adamski A;Abe K;Reyes NL;Richardson LC;Hooper WC;Schieve LA
关于脑静脉窦血栓形成（CVST）的基于人群的数据有限。调查CVST在美国的流行病学。分析了三个管理数据系统：2018年医疗成本和利用项目全国住院患者样本（NIS），2019年IBM MarketScan商业和医疗保险补充索赔数据库，以及2019年IBM MarketScan多州医疗补助数据库。采用国际疾病分类第十版临床修改代码确定CVST、血小板减少症和多种合并症。估计了CVST和CVST伴血小板减少症的发生率（每100，000总美国人群[NIS]和每100，000相关贡献健康计划覆盖的0至64岁人群[MarketScan样本]）。估计了NIS样本中CVST病例与总住院患者的合并症患病率。估计了市售样本的近期妊娠率。NIS、商业和医疗补助样本中CVST的发生率分别为2.85、2.45和3.16。CVST伴血小板减少的发生率分别为0.21、0.22和0.16。在所有样本中，CVST的发病率随年龄的增长而增加;然而，女性的发病率峰值出现在比男性更年轻的年龄。与普通住院人群相比，CVST患者的出血性卒中、缺血性卒中、其他静脉血栓栓塞（VTE）、中枢神经系统感染、头颈部感染、既往VTE、血栓形成倾向、恶性肿瘤、头部损伤、出血性疾病和结缔组织疾病的患病率较高。年龄在18至49岁之间的CVST女性的妊娠患病率高于相同年龄的一般人群。我们的研究结果提供了CVST和CVST伴血小板减少症流行病学的最新和全面的数据。
Population‐based data about cerebral venous sinus thrombosis (CVST) are limited. To investigate the epidemiology of CVST in the United States. Three administrative data systems were analyzed: the 2018 Healthcare Cost and Utilization Project National Inpatient Sample (NIS) the 2019 IBM MarketScan Commercial and Medicare Supplemental Claims Database, and the 2019 IBM MarketScan Multi‐state Medicaid Database. CVST, thrombocytopenia, and numerous comorbidities were identified using the International Classification of Diseases, Tenth Revision, Clinical Modification codes. Incidence rates of CVST and CVST with thrombocytopenia were estimated (per 100,000 total US population [NIS] and per 100,000 population aged 0 to 64 years covered by relevant contributing health plans [MarketScan samples]). Comorbidity prevalence was estimated among CVST cases versus total inpatients in the NIS sample. Recent pregnancy prevalence was estimated for the Commercial sample. Incidence rates of CVST in NIS, Commercial, and Medicaid samples were 2.85, 2.45, and 3.16, respectively. Incidence rates of CVST with thrombocytopenia were 0.21, 0.22, and 0.16, respectively. In all samples, CVST incidence increased with age; however, peak incidence was reached at younger ages in females than males. Compared with the general inpatient population, persons with CVST had higher prevalences of hemorrhagic stroke, ischemic stroke, other venous thromboembolism (VTE), central nervous system infection, head or neck infection, prior VTE, thrombophilia, malignancy, head injury, hemorrhagic disorder, and connective tissue disorders. Women aged 18 to 49 years with CVST had a higher pregnancy prevalence than the same‐aged general population. Our findings provide recent and comprehensive data on the epidemiology of CVST and CVST with thrombocytopenia.
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影响因子：
33.9
作者：
Shay, David K.;Gee, Julianne;Su, John R.;Myers, Tanya R.;Marquez, Paige;Liu, Ruiling;Zhang, Bicheng;Licata, Charles;Clark, Thomas A.;Shimabukuro, Tom T.
通讯作者：
Shimabukuro, Tom T.
DOI：
10.1056/nejmoa2104840
发表时间：
2021-06-03
期刊：
The New England journal of medicine
影响因子：
--
作者：
Greinacher A;Thiele T;Warkentin TE;Weisser K;Kyrle PA;Eichinger S
通讯作者：
Eichinger S
影响因子：
3.2
作者：
Handley, Joel D.;Emsley, Hedley C. A.
通讯作者：
Emsley, Hedley C. A.
影响因子：
120.7
作者：
See, Isaac;Su, John R.;Broder, Karen R.
通讯作者：
Broder, Karen R.
影响因子：
8.3
作者：
Coutinho, Jonathan M.;Zuurbier, Susanna M.;Stam, Jan
通讯作者：
Stam, Jan