INVIVO AND EXVIVO MAGNETIC-RESONANCE-IMAGING EVALUATION OF EARLY DISK DEGENERATION WITH HISTOPATHOLOGIC CORRELATION
INVIVO AND EXVIVO MAGNETIC-RESONANCE-IMAGING EVALUATION OF EARLY DISK DEGENERATION WITH HISTOPATHOLOGIC CORRELATION
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DOI：
10.1097/00007632-199106000-00007
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发表时间：
1991-06-01
期刊：
影响因子：
3
通讯作者：
KRESSEL, HY
中科院分区：
文献类型：
--
作者：
SCHIEBLER, ML;CAMERINO, VJ;KRESSEL, HY
通过磁共振成像确定早期椎间盘退变的体内和体外显微解剖表现，并与各自的组织病理学结果相关联。研究了5个身体脊柱(18个椎体)和25个患者研究(122个椎体)，均以1.5 Tesia的速度成像。发现两种早期退行性腰椎间盘疾病的征象：内折和中心点。外环中央纤维的折叠融合成一个低信号强度的中心点，这在体外和体内图像上都可以看到。122次中有29次可见内折叠，122次中有15次可见中心点。后一种退行性腰椎间盘疾病被确认为髓核与透明软骨终板分离。这种分离在体外图像上被视为低或高信号强度的线性区域，但在体内自旋回波2,500毫秒/80毫秒图像上仅被视为高信号强度带。在122个活体圆盘中，只有7个显示了这种分离。只有在活体图像上才能看到髓核内突出进入外环。在长重复时间(TR)/回声时间(TE)磁共振图像上的椎间盘高度或信号强度丢失之前，可能存在早期退行性腰椎间盘疾病。
The in vivo and ex vivo microanatomic appearance of early disc degeneration were identified by magnetic resonance imaging and correlated with their respective histopathologic findings. Five cadaver spines (18 discs) and 25 patient studies (122 discs) all imaged at 1.5 Tesia were studied. Two signs of early degenerative disc disease were found: infolding and the central dot. Infolding of the central fibers of the outer annulus coalesced into a central dot of low signal intensity that was seen on both the ex vivo and in vivo images. Infolding was seen 29 of 122 times, and the central dot was observed 15 of 122 times on the in vivo images. A later form of degenerative disc disease was identified as a separation of the nucleus pulposus from the hyaline cartilage end-plate. This separation was seen as a linear area of either low or high signal intensity on the ex vivo images but only as a band of high signal intensity on the in vivo spin-echo 2,500-msec/80-msec images. Only 7 of 122 in vivo discs showed this separation. Internal herniation of nucleus pulposus into the outer annulus was seen only on the ex vivo images. Early degenerative disc disease may exist before there is loss of disc height or signal intensity on the long time-to-repetition (TR)/time-to-echo (TE) magnetic resonance images.