GENETICS OF SPECIFIC READING-DISABILITY

GENETICS OF SPECIFIC READING-DISABILITY
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DOI:
10.1111/j.1469-1809.1976.tb00161.x
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发表时间:
1976-01-01
影响因子:
1.9
通讯作者:
CHILDS, B
CHILDS, B
中科院分区:
生物学4区
文献类型:
--
作者:
FINUCCI, JM;GUTHRIE, JT;CHILDS, B

文献摘要

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对20名患有特定阅读障碍的儿童的直系亲属进行了检查,以确定家庭中阅读障碍的患病率。制定了一项程序,以确定可能对儿童时期表现得更明显的残疾给予补偿的成年人。在父母的75名一级亲属中,45%受到影响,受影响的男性亲属人数明显多于女性。在对家系进行检查后,没有发现单一的遗传传播模式。这种疾病是遗传异质性和亚组的残疾读者应寻求。
Members of the immediate families of 20 children with specific reading disability were examined to determine the prevalence of reading disability within the families. A procedure was developed for identifying adults who may have compensated for a disability manifested more clearly in childhood. Of 75 1st-degree relatives of the parents, 45% were affected and there was a significantly greater number of affected male relatives than females. No single mode of genetic transmission was evident after inspection of the pedigrees. The disorder was genetically heterogeneous and subgroups of disabled readers should be sought.