X-change symposium: status and future of modern radiation oncology-from technology to biology.
X-change symposium: status and future of modern radiation oncology-from technology to biology.
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X变化研讨会：现代辐射肿瘤从生物学技术中的状态和未来。
DOI：
10.1186/s13014-021-01758-w
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发表时间：
2021-02-04
期刊：
影响因子：
--
通讯作者：
Belka C
中科院分区：
文献类型：
--
作者：
Corradini S;Niyazi M;Verellen D;Valentini V;Walsh S;Grosu AL;Lauber K;Giaccia A;Unger K;Debus J;Pieters BR;Guckenberger M;Senan S;Budach W;Rad R;Mayerle J;Belka C
未来的放射肿瘤学涵盖了从现代临床试验设计到治疗、成像技术和生物学的广泛主题。更详细地说，混合核磁共振设备在现代影像引导放射治疗中的应用；放射组学的新兴领域；使用正电子发射断层扫描的分子成像的作用及其与临床常规的整合；放射生物学及其未来前景；分子标记在预后建模中的作用；以及特殊治疗方式，如近距离放射治疗或质子束治疗，都是快速发展的领域。在临床上，放射肿瘤学肯定会在治疗少转移瘤中发挥重要作用。通过将现代系统靶向或免疫疗法合理地整合到多模式治疗策略中，治疗范围也将扩大。所有这些发展都需要对临床试验设计进行简明的重新思考。本文回顾了欧洲和国际专家小组在2019年7月于德国慕尼黑举行的“X-Change”专题讨论会上讨论的放射肿瘤学领域的现状和潜在发展。
Future radiation oncology encompasses a broad spectrum of topics ranging from modern clinical trial design to treatment and imaging technology and biology. In more detail, the application of hybrid MRI devices in modern image-guided radiotherapy; the emerging field of radiomics; the role of molecular imaging using positron emission tomography and its integration into clinical routine; radiation biology with its future perspectives, the role of molecular signatures in prognostic modelling; as well as special treatment modalities such as brachytherapy or proton beam therapy are areas of rapid development. More clinically, radiation oncology will certainly find an important role in the management of oligometastasis. The treatment spectrum will also be widened by the rational integration of modern systemic targeted or immune therapies into multimodal treatment strategies. All these developments will require a concise rethinking of clinical trial design. This article reviews the current status and the potential developments in the field of radiation oncology as discussed by a panel of European and international experts sharing their vision during the “X-Change” symposium, held in July 2019 in Munich (Germany).
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影响因子：
2.8
作者：
Carl G;Reitz D;Schönecker S;Pazos M;Freislederer P;Reiner M;Alongi F;Niyazi M;Ganswindt U;Belka C;Corradini S
通讯作者：
Corradini S
通过辐射和靶向AXL重新编程免疫学微环境。
影响因子：
16.6
作者：
通讯作者：
--
影响因子：
2.9
作者：
Bothwell LE;Avorn J;Khan NF;Kesselheim AS
通讯作者：
Kesselheim AS
影响因子：
20.4
作者：
De Ruysscher, Dirk;Wanders, Rinus;Dingemans, Anne-Marie C.
通讯作者：
Dingemans, Anne-Marie C.
影响因子：
8.9
作者：
Cusumano, Davide;Dinapoli, Nicola;Valentini, Vincenzo
通讯作者：
Valentini, Vincenzo