Apoptosis as a proinflammatory event: what can we learn from bacteria-induced cell death?
Apoptosis as a proinflammatory event: what can we learn from bacteria-induced cell death?
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DOI：
10.1016/s0966-842x(97)01044-5
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发表时间：
1997-05
影响因子：
15.9
通讯作者：
A. Zychlinsky;P. Sansonetti
中科院分区：
文献类型：
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作者：
A. Zychlinsky;P. Sansonetti
某些病原菌感染细胞会引发宿主细胞凋亡。细菌诱导的细胞凋亡似乎促进炎症反应，导致组织损伤和进一步的细菌定植。志贺氏菌的发病机制为细胞凋亡在细菌感染中的作用提供了一个范例。
Infection of cells by some pathogenic bacteria triggers host cell apoptosis. Bacteria-induced apoptosis appears to promote an inflammatory response that causes tissue damage and further bacterial colonization. Shigella pathogenesis offers a paradigm for the role of apoptosis in bacterial infections.