Estimating regions of air trapping from electrical impedance tomography data.

Estimating regions of air trapping from electrical impedance tomography data.
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DOI:
10.1088/1361-6579/aac295
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发表时间:
2018-05-31
影响因子:
3.2
通讯作者:
DeBoer E
DeBoer E
中科院分区:
工程技术3区
文献类型:
--
作者:
Mueller JL;Muller P;Mellenthin M;Murthy R;Capps M;Alsaker M;Deterding R;Sagel SD;DeBoer E

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电阻抗断层成像(EIT)已被证明是一种可行的非侵入性,床旁成像方式来监测肺功能。本文介绍了一种方法,从EIT数据收集的潮气呼吸和屏气演习中识别区域的空气截留。根据动态EIT图像计算通气-灌注指数图。然后,这些图用于将肺区域中的空气滞留区域识别为通气不良但在整个呼吸和心动周期中灌注良好的区域。然后将这些EIT识别的区域与胸部CT上独立识别的低衰减或空气滞留区域进行比较。该方法的结果在两名患有囊性纤维化的儿童和一名健康对照受试者中得到证实。在这两个CF儿童中,EIT识别的空气滞留区域与胸部CT显示的区域相匹配。基于EIT的方法仅通过电极平面定义的胸部横截面4 cm内的CT扫描进行验证。结果表明,EIT衍生的通气-灌注指数图作为一种非侵入性方法,用于识别空气滞留区域的潜在用途。
Electrical impedance tomography (EIT) has been shown as a viable non-invasive, bedside imaging modality to monitor lung function.This paper introduces a method for identifying regions of air trapping from EIT data collected during tidal breathing and breath-holding maneuvers. Ventilation-perfusion index maps are computed from dynamic EIT images. These maps are then used to identify regions of air trapping in the area of the lung as regions that are poorly ventilated but well perfused throughout the breathing and cardiac cycles. These EIT-identified regions are then compared with independently identified regions of low attenuation, or air trapping, on chest CT. Results of this method are demonstrated in two children with cystic fibrosis and on a healthy control subject. In both CF children, the EIT-identified regions of air trapping matched the regions indicated from the chest CT. The EIT-based method is only validated with CT scans within 4 cm of the chest cross-section defined by the electrode plane. The results indicate the potential use of EIT-derived ventilation-perfusion index maps as a non-invasive method for identifying regions of air trapping.
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发表时间: 2017-01-01
影响因子: 14.2
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