Cardiovascular recovery from psychological and physiological challenge and risk for adverse cardiovascular outcomes and all-cause mortality.
Cardiovascular recovery from psychological and physiological challenge and risk for adverse cardiovascular outcomes and all-cause mortality.
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从心理和生理挑战以及不良心血管结局和全因死亡率风险中恢复心血管。
DOI：
10.1097/psy.0000000000000171
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发表时间：
2015
影响因子：
3.3
通讯作者：
Rottenberg,Jonathan
中科院分区：
文献类型：
--
作者：
Panaite,Vanessa;Salomon,Kristen;Jin,Alvin;Rottenberg,Jonathan
心血管（CV）对实验室挑战的反应性被证明可以预测未来的CV发病率和死亡率。CV恢复的研究较少，并产生了不一致的结果，可能是由于主持人的存在。关于CV恢复和CV结局之间关系的综述仅限于横断面研究，未考虑方法学因素。我们进行了全面的荟萃分析审查的前瞻性文献调查CV恢复到身体和心理的挑战和不良CV outcomes.MethodsWe搜索PsycINFO和PubMed的前瞻性研究调查CV恢复和不良CV结局之间的关系。研究被编码为感兴趣的变量和效应量。我们进行了随机效应加权荟萃分析。主持人进行了检查，方差模拟和荟萃回归analysis.ResultsThirty-seven研究符合纳入标准（n= 125,386）的分析。从挑战中恢复受损预测不良CV结局（汇总效应，r= 0.17，p<0.05）。001）。身体挑战比心理挑战具有更大的预测效应。主持人分析显示，恢复测量1分钟postexercise，被动恢复，使用死亡率作为一个结果的措施，和老年人样本年龄与较大的effects.Conclusionspoor recovery从实验室的挑战预测不利的心血管结局，从运动中恢复作为一个特别强的预测心血管结局。恢复和CV结局的总体效应量与观察到的CV反应性相似，表明恢复研究可能对了解不良CV结局具有增量价值。
ObjectiveExaggerated cardiovascular (CV) reactivity to laboratory challenge has been shown to predict future CV morbidity and mortality. CV recovery has been less studied and has yielded inconsistent findings, possibly due to the presence of moderators. Reviews on the relationship between CV recovery and CV outcomes have been limited to cross-sectional studies and have not considered methodological factors. We performed a comprehensive meta-analytic review of the prospective literature investigating CV recovery to physical and psychological challenge and adverse CV outcomes.MethodsWe searched PsycINFO and PubMed for prospective studies investigating the relationship between CV recovery and adverse CV outcomes. Studies were coded for variables of interest and for effect sizes. We conducted a random-effects weighted meta-analysis. Moderators were examined with analysis of variance–analog and meta-regression analyses.ResultsThirty-seven studies met the inclusion criteria (n= 125,386). Impaired recovery from a challenge predicted adverse CV outcomes (summary effect, r= 0.17, p<. 001). Physical challenge was associated with larger predictive effects than psychological challenge. Moderator analyses revealed that recovery measured at 1 minute postexercise, passive recovery, use of mortality as an outcome measure, and older sample age were associated with larger effects.ConclusionsPoor recovery from laboratory challenges predicts adverse CV outcomes, with recovery from exercise serving as a particularly strong predictor of CV outcomes. The overall effect size for recovery and CV outcomes is similar to that observed for CV reactivity and suggests that the study of recovery may have incremental value for understanding adverse CV outcomes.