Microarray-based optimization to detect genomic deletion mutations.
Microarray-based optimization to detect genomic deletion mutations.
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DOI：
10.1016/j.gdata.2014.04.005
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发表时间：
2014-12
期刊：
影响因子：
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通讯作者：
Harberd NP
中科院分区：
文献类型：
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作者：
Belfield EJ;Brown C;Gan X;Jiang C;Baban D;Mithani A;Mott R;Ragoussis J;Harberd NP
我们进行了阵列比较基因组杂交（aCGH）分析的五个拟南芥突变体的基因组缺失的大小从4 bp到> 5 kb。我们使用Roche NimbleGen Arabidopsis CGH 3 × 720 K全基因组定制平铺阵列来优化缺失检测。微阵列设计和杂交数据的细节已经以登录号GSE 55327保藏在NCBI GEO储存库中。
We performed array comparative genome hybridization (aCGH) analyses of five Arabidopsis thaliana mutants with genomic deletions ranging in size from 4 bp to > 5 kb. We used the Roche NimbleGen Arabidopsis CGH 3 × 720 K whole genome custom tiling array to optimize deletion detection. Details of the microarray design and hybridization data have been deposited at the NCBI GEO repository with accession number GSE55327.