Prevalence of and Factors Associated with the Use of HIV Serosorting and Other Biomedical Prevention Strategies Among Men Who Have Sex with Men in a US Nationwide Survey.
Prevalence of and Factors Associated with the Use of HIV Serosorting and Other Biomedical Prevention Strategies Among Men Who Have Sex with Men in a US Nationwide Survey.
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DOI：
10.1007/s10461-018-2084-7
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发表时间：
2018-08
影响因子：
4.4
通讯作者：
Parsons JT
中科院分区：
文献类型：
--
作者：
Grov C;Jonathan Rendina H;Patel VV;Kelvin E;Anastos K;Parsons JT
PrEP和治疗即预防（TasP）是减少艾滋病毒传播的生物医学战略。一些男男性行为者（MSM）正在将生物医学策略与艾滋病毒血清分选相结合-当双方都使用PrEP或TasP时称为“生物医学匹配”，或者当一方使用PrEP和另一方使用TasP时称为“生物医学分选”。然而，有有限的数据在大的地理多样性样本的生物匹配/排序的程度。在2016-2017年，来自美国各地的5，021名MSM接受了关于他们的艾滋病毒状况和艾滋病毒载量/PrEP使用情况的调查，以及他们最近的临时男性伴侣。对于每个参与者，我们计算了他的伴侣的比例（1）艾滋病毒阳性和不可检测，（2）艾滋病毒阳性和可检测/未知，（3）艾滋病毒未知/未讨论，（4）艾滋病毒阴性的PrEP，（5）艾滋病毒阴性，而不是PrEP。14.1%（n=707）HIV阳性和不可检测，1.1%（n=55）HIV阳性和病毒载量可检测/未知，6.2%（n=313）HIV不确定/未知。参与者自身的HIV和PrEP状态与其伴侣的HIV和PrEP状态显著相关（所有p<0.001），表明血清分选和生物医学匹配的证据。在接受PrEP治疗的男性和艾滋病毒检测不到的男性中，也有一些证据表明这些参与者同时参与了生物医学匹配和生物医学分类。我们发现了生物医学匹配和分类的证据，这可能会增加其对使用者的有效性（即，双方都提供生物医学保护）。生物医学匹配/排序的意外后果包括，不使用生物医学策略的男性可能不太可能从伴侣使用该策略中受益，这可能进一步推动艾滋病毒感染的差异。公共卫生运动可能不仅有助于强调生物医学艾滋病毒预防战略为其使用者提供的好处（例如，“使用PrEP可以保护我免受艾滋病毒感染”），而且还可以保护用户给其伴侣带来的好处（例如，“我使用PrEP意味着我的伴侣不会感染艾滋病毒”），以及与使用生物医学策略的伴侣在一起的好处（例如，“我的伴侣使用PrEP/TasP可以保护我免受艾滋病毒感染”）。
PrEP and Treatment-as-Prevention (TasP) are biomedical strategies to reduce HIV transmission. Some men who have sex with men (MSM) are combining biomedical strategies with HIV serosorting–termed “biomed matching” when both partners are either on PrEP or TasP, or “biomed sorting” when one partner is using PrEP and the other TasP. Nevertheless, there is limited data on the extent of biomed matching/sorting in large geographically diverse samples. In 2016-2017, 5,021 MSM from across the US were surveyed about their HIV status and HIV viral load/PrEP use, as well as that of their recent casual male partners. For each participant, we calculated the proportion of his partners who were (1) HIV-positive and undetectable, (2) HIV-positive and detectable/unknown, (3) HIV unknown/undiscussed, (4) HIV-negative on PrEP, (5) HIV-negative, not on PrEP. In total, 66.6% (n=3346) of participants were HIV-negative and not on PrEP, 11.9% (n=599) on PrEP, 14.1% (n=707) HIV-positive and undetectable, 1.1% (n=55) HIV-positive and viral load detectable/unknown, and 6.2% (n=313) HIV unsure/unknown. A participant’s own HIV and PrEP status/was significantly associated with that of his partners (all p<.001), evincing evidence of both serosorting and biomed matching. Among men on PrEP and those who were HIV-undetectable, there was also some evidence to suggest these participants dually engaged in biomed matching as well as biomed sorting. We found evidence of biomed matching and sorting, which may compound its effectiveness for those using it (i.e., both partners bring biomedical protection). Unintended consequences of biomed matching/sorting include that men not using a biomedical strategy may be less likely to benefit from a partner’s use of the strategy—potentially further driving disparities in HIV infections. Public health campaigns might be well served to highlight not only the benefits that biomedical HIV prevention strategies provide for their users (e.g., “being on PrEP protects me from getting HIV”), but also the benefits that a user brings to his partners (e.g., “my use of PrEP means my partners won’t get HIV”), and the benefits of being with a partner who is using a biomedical strategy (e.g., “my partner’s use of PrEP/TasP protects me from HIV”).
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DOI：
10.1007/s13178-015-0212-y
发表时间：
2016-03-01
期刊：
Sexuality research & social policy : journal of NSRC : SR & SP
影响因子：
--
作者：
Grov C;Cain D;Whitfield TH;Rendina HJ;Pawson M;Ventuneac A;Parsons JT
通讯作者：
Parsons JT
影响因子：
3.8
作者：
Dubois-Arber, Francoise;Jeannin, Andre;Balthasar, Hugues
通讯作者：
Balthasar, Hugues
影响因子：
3.8
作者：
Berry, Mark;Raymond, H. Fisher;McFarland, Willi
通讯作者：
McFarland, Willi
DOI：
10.1521/aeap.2016.28.5.378
发表时间：
2016-10
期刊：
AIDS education and prevention : official publication of the International Society for AIDS Education
影响因子：
--
作者：
Grov C;Rendina HJ;Jimenez R;Parsons JT
通讯作者：
Parsons JT
影响因子：
3.7
作者：
Ackers ML;Greenberg AE;Lin CY;Bartholow BN;Goodman AH;Longhi M;Gurwith M
通讯作者：
Gurwith M