Incidence of stroke and season of the year: Evidence of an association
Incidence of stroke and season of the year: Evidence of an association
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DOI：
10.1093/aje/152.6.558
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发表时间：
2000-09-15
影响因子：
5
通讯作者：
Horner, RD
中科院分区：
文献类型：
--
作者：
Oberg, AL;Ferguson, JA;Horner, RD
中风发病率季节性变化的证据是不一致的。这可能是调查这一问题的研究的一个或多个方法缺陷的结果，包括不适当的分析模型，时间不够长，样本量小，以及区域（相对于国家）重点。作者的目的是通过使用一种旨在克服这些局限性的方法学方法来确定一年中的季节与卒中发病率之间是否存在关联。作者采用纵向研究设计，涉及1986年至1995年期间在全国任何退伍军人事务医院因中风住院的72，779名退伍军人。这些数据进行了分析，采用时间序列方法。有明确的证据表明，中风一般具有季节性。这种季节性效应在缺血性中风中发现，但在出血性中风中没有发现。5月中旬为发病高峰期。该地区（即，气候），也没有病人的种族实质上改变了季节性趋势。对这一模式的解释尚待确定。
Evidence of seasonal variation in the incidence of stroke is inconsistent. This may be a likely consequence of one or more methodological shortcomings of the studies investigating this issue, including inappropriate analytic models, insufficient length of time, small sample size, and a regional (vs. national) focus. The authors' objective was to ascertain whether an association exists between season of the year and the incidence of stroke by using a methodological approach designed to overcome these limitations. The authors used a longitudinal study design involving 72,779 veterans hospitalized for stroke at any Veterans Affairs hospital nationally during the years 1986-1995. These data were analyzed by using time series methods. There was clear evidence of a seasonal occurrence for stroke in general. This seasonal effect was found for ischemic stroke, but not for hemorrhagic stroke. The peak occurrence was in mid-May. Neither the region (i.e., climate) nor the race of the patient substantially modified the seasonal trend. An explanation for this pattern remains to be determined.