Effects of oral administration of maltitol on plasma glucose, plasma sorbitol, and serum insulin levels in man
Effects of oral administration of maltitol on plasma glucose, plasma sorbitol, and serum insulin levels in man
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口服麦芽糖醇对人体血糖、血浆山梨醇和血清胰岛素水平的影响
DOI：
10.1007/bf01711933
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发表时间：
1986
期刊：
影响因子：
--
通讯作者：
G. Pozza
中科院分区：
文献类型：
--
作者：
A. Secchi;A. Pontiroli;L. Cammelli;A. Bizzi;M. Cini;G. Pozza
本研究旨在研究急性和慢性口服麦芽糖醇（4-O-i-d-吡喃葡萄糖基-d-葡萄糖醇）的代谢效应，麦芽糖醇是一种低热量的甜味剂，由麦芽糖催化氢化而得。50克麦芽糖醇比相同剂量的葡萄糖或蔗糖诱导低血糖和胰岛素血症的增加。180分钟后，观察到血浆葡萄糖和血清胰岛素水平没有变化。麦芽糖醇后45分钟，观察到血浆麦芽糖醇略有增加。与相同剂量的蔗糖相比，长期给予麦芽糖醇（10 g，每日3次，共5天）未引起胰岛素或胰岛素血症的变化。麦芽糖醇后血浆山梨醇水平略高于蔗糖后。在尿液和粪便中检测到少量麦芽糖醇。
The present study was aimed to investigate the metabolic effects of acute and chronic oral administration of maltitol (4-O-i-d-glucopyranosyl-d-glucitol), a hypocaloric sweetener obtained from maltose by catalytic hydrogenation. Fifty grams of maltitol induced a increase lower glycemic and insulinemic than the same dose of glucose or sucrose. No variations of plasma glucose and serum insulin levels were observed after 180 min. A slight increase of plasma maltitol was observed 45 min after maltitol. The chronic administration of maltitol (10 g 3× daily for 5 days) induced no variations of glycemia or insulinemia when compared with the same dose of sucrose. Plasma sorbitol levels were slightly higher after maltitol than after sucrose. Low amounts of maltitol were detected in the urine and feces.