[Environmental factors influencing sensitization and onset of Japanese cedar pollinosis among junior high school students].
[Environmental factors influencing sensitization and onset of Japanese cedar pollinosis among junior high school students].
复制标题
影响初中生柳杉花粉病致敏和发病的环境因素[J].
DOI：
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发表时间：
1996
期刊：
影响因子：
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通讯作者：
M. Fujioka
中科院分区：
文献类型：
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作者：
H. Kato;Y. Mizuno;M. Yamazaki;N. Ishikawa;M. Fujioka
日本雪松花粉症在城市地区而不是农村地区有很大的增加，特别是在年轻人中增加得很明显。为了阐明日本雪松花粉症的致敏和发病因素，对居住在三个不同地区的初中生进行了问卷调查并检测了血清IgE抗体水平，即，爱知县的城市、海滨和山区。日本雪松花粉症的患病率，估计从有鼻或眼过敏症状和阳性RAST的学生人数，是30.1%的山区与日本雪松花粉计数高，大于15.3%的城市地区和5.8%的海滨地区，都与低花粉计数。在显示高血清螨（粉尘螨）抗体水平的学生中，观察到日本雪松或果园草花粉致敏的阳性率更高，与螨未致敏的学生相比。这一结果表明，对季节性抗原的致敏性可能与对螨的致敏能力相对应。此外，对问卷调查的分析表明，居住在混凝土或钢架建筑物中的学生血清中的日本雪松花粉抗体水平高于居住在木结构建筑物中的学生，这表明花粉致敏性与室内环境之间可能存在关系。
Japanese cedar pollinosis has shown large increases especially in city areas, rather than in the rural, with increases being remarkable especially among people of young age. In order to elucidate factors for sensitization and onset of Japanese cedar pollinosis, a questionnaire survey was conducted and serum IgE antibody levels examined in junior high school students living in three different areas, i.e., city, seaside and mountainous areas in Aichi prefecture. Prevalence rate of Japanese cedar pollinosis, estimated from the number of students having both nasal or ocular allergic symptoms and positive RAST, was the 30.1% in the mountainous area with high Japanese cedar pollen count, being greater than the 15.3% in the city area and the 5.8% in the seaside area, both with low pollen counts. Among the students showing high serum mite (Dermatophagoides farinae) antibody levels, greater positive rates for sensitization to Japanese cedar or orchard grass pollens was observed, compared to mite-unsensitized students. This result suggests that sensitization to seasonal antigens may be corresponding to the capability for sensitization to the mites. Besides this finding, the analysis of replies to the questionnaires showed that students living in concrete or steel-frame buildings had greater serum levels of antibody to Japanese cedar pollen than those living in wood buildings, indicating a possible relationship between the pollen sensitization and indoor environments.