Application of carbon nanoparticles combined with intraoperative neuromonitoring in papillary thyroid microcarcinoma surgery
Application of carbon nanoparticles combined with intraoperative neuromonitoring in papillary thyroid microcarcinoma surgery
复制标题
纳米碳联合术中神经监测在甲状腺微小乳头状癌手术中的应用
DOI：
10.1016/j.amjoto.2020.102790
复制
发表时间：
2021-01-01
影响因子：
2.5
通讯作者：
Liu, Xuemei
中科院分区：
文献类型：
--
作者：
Li, Taolang;Ma, Zhiyuan;Liu, Xuemei
目的：为了提高淋巴结清扫效果并保护甲状旁腺和喉返神经，将纳米碳和术中神经监测应用于甲状腺微小乳头状癌手术。方法：实验组使用纳米碳和术中神经监测，对照组不使用纳米碳和术中神经监测。常规进行病理检查。结果：实验组清扫的淋巴结明显增多，但转移淋巴结没有明显增多。实验组误解剖甲状旁腺和术后甲状旁腺功能减退的数量分别为3个和13个，明显少于对照组的10个和25个。实验组总体、短暂性和持续性喉返神经麻痹的发生率分别为5.5%、5.5%和0%，而对照组分别为8.6%、6.9%和1.7%。结论：纳米碳可以改善甲状腺微小乳头状癌手术中的淋巴结清扫，纳米碳与术中神经监测相结合可以减少手术并发症，提高患者生活质量。
Purposes: To improve the lymph node dissection as well as protect parathyroid gland and recurrent laryngeal nerve, the carbon nanoparticles and intraoperative neuromonitoring were applied in papillary thyroid micro carcinoma surgery.Methods: Carbon nanoparticles and intraoperative neuromonitoring were used in the experimental group, whereas the control group were not. Routine pathological examination was performed.Results: The lymph nodes dissected was significantly higher in the experimental group, but the metastatic lymph nodes were not. The number of mistakenly dissected parathyroid gland and postoperative hypoparathyroidism were 3 and 13 in the experimental group respectively, significantly less than 10 and 25 in the control group. The incidences of overall, transient and persistent recurrent laryngeal nerve palsy in the experimental group were 5.5%, 5.5% and 0% respectively, whereas in the control group were 8.6%, 6.9% and 1.7%.Conclusions: Carbon nanoparticles can improve lymph node dissection in papillary thyroid microcarcinoma surgery, and the combination of carbon nanoparticles with intraoperative neuromonitoring can reduce surgical complications and improve patient quality of life.