Suppression of 18F-FDG Myocardial Uptake Using a Fat-Allowed, Carbohydrate-Restricted Diet
Suppression of 18F-FDG Myocardial Uptake Using a Fat-Allowed, Carbohydrate-Restricted Diet
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DOI：
10.2967/jnmt.110.076489
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发表时间：
2011-09-01
影响因子：
1.3
通讯作者：
Roef, Mark
中科院分区：
文献类型：
--
作者：
Balink, Hans;Hut, Evelien;Roef, Mark
通常采用禁食方案的患者心肌F-18-FDG摄取变化，这可能导致难以解释纵隔F-18-FDG摄取。这项回顾性研究描述了1天脂肪允许、碳水化合物限制饮食对心肌F-18-FDG摄取的影响。方法：该研究包括100名来自Leeuwarden医学中心的限制碳水化合物饮食的患者和100名来自乌得勒支大学医学中心的无限制饮食的患者。采用视觉摄取量表，第0类表明心肌摄取少于肝脏摄取，第1类表明心肌摄取与肝脏摄取相当，第2类表明心肌摄取明显高于肝脏摄取。结果：在限制碳水化合物饮食后，68%的患者F-18-FDG的心肌摄取均为低（0类），14%的患者心肌摄取中度（1类），18%的患者心肌摄取均为强烈（2类）。在不限制碳水化合物饮食的情况下，69%的患者表现为均匀强烈的心肌摄取（2类），16%的患者表现为中度心肌摄取（1类），15%的患者表现为均匀低心肌摄取（0类）。结论：在给予f18 - fdg前一天开始的允许脂肪、限制碳水化合物的饮食可以令人满意地抑制心肌对f18 - fdg的摄取。
Patients prepared by the generally used fasting protocol show variable myocardial F-18-FDG uptake, which may result in difficult interpretation of mediastinal F-18-FDG uptake. This retrospective study described the effect of a 1-d fat-allowed, carbohydrate-restricted diet onmyocardial F-18-FDG uptake. Methods: The study included 100 patients on a carbohydrate-restricted diet from the Medical Center Leeuwarden and 100 patients on an unrestricted diet from the University Medical Center of Utrecht. A visual uptake scale was used, with category 0 indicating myocardial uptake less than liver uptake, category 1 indicating myocardial uptake comparable to liver uptake, and category 2 indicating myocardial uptake considerably higher than liver uptake. Results: After a carbohydrate-restricted diet, 68% of patients had a homogeneously low myocardial uptake of F-18-FDG (category 0), 14% had moderate myocardial uptake (category 1), and 18% had homogeneously intense myocardial uptake (category 2). Without a carbohydrate-restricted diet, 69% of patients showed a homogeneously intense myocardial uptake (category 2), 16% a moderate myocardial uptake (category 1), and 15% a homogeneously low myocardial uptake (category 0). Conclusion: A fat-allowed, carbohydrate-restricted diet starting the day before F-18-FDG administration suppresses myocardial F-18-FDG uptake satisfactorily.