Amyotrophic lateral sclerosis in the Mariana Islands.
Amyotrophic lateral sclerosis in the Mariana Islands.
复制标题
马里亚纳群岛的肌萎缩侧索硬化症。
DOI：
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发表时间：
1956
期刊：
影响因子：
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通讯作者：
D. W. Mulder
中科院分区：
文献类型：
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作者：
L. Kurland;D. W. Mulder
Arnold 及其同事（1949 年）和 Koerner（1952 年）关于关岛肌萎缩侧索硬化症病例集中的报告引发了一项调查，以确认诊断，并在可能的情况下解释这一现象。展览中展示了迄今为止已完成的许多研究结果。该展览展示了马里亚纳群岛该疾病的主要临床和病理特征，并揭示了它是一种典型的肌萎缩侧索硬化症，具有高家族发病率。为了与马里亚纳群岛的结果进行比较，肌萎缩侧索硬化症的基线患病率数据是通过死亡率统计数据和明尼苏达州罗彻斯特的调查数据从美国、加拿大和几个欧洲国家获得的。估计这些地区每 10 万人中有 4 至 6 人患有肌萎缩侧索硬化症。然而，估计查莫罗人（原住民）中的患病率
THE REPORT of the concentration of cases of amyotrophic lateral sclerosis on the Island of Guam by Arnold and associates (1949) and by Koerner (1952) led to an investigation to confirm the diagnosis and, if possible, to explain this phenomenon. Many of the results of the study so far completed are illustrated in the exhibit. The exhibit demonstrates the principal clinical and pathological features of the disease in the Mariana Islands and reveals that it is a classic form of amyotrophic lateral sclerosis with a high familial incidence. Base-line prevalence data for amyotrophic lateral sclerosis for comparison with the results in the Mariana Islands were obtained from the United States, Canada, and several European countries through mortality statistics and through survey data in Rochester, Minn. It was estimated as 4 to 6 per 100,000 population in these areas. However, the estimated prevalence among the Chamorro people (original natives) in the