Peptic ulcers after the Hanshin-Awaji earthquake: Increased incidence of bleeding gastric ulcers
Peptic ulcers after the Hanshin-Awaji earthquake: Increased incidence of bleeding gastric ulcers
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DOI：
10.1111/j.1572-0241.1998.00311.x
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发表时间：
1998-03-01
影响因子：
9.8
通讯作者：
Chiba, T
中科院分区：
文献类型：
--
作者：
Aoyama, N;Kinoshita, Y;Chiba, T
目的：虽然已知生理应激可诱发上消化道消化性溃疡，但情绪应激是否可导致消化性溃疡仍存在争议。因此，我们回顾性研究了1995年1月日本坂神淡路地震对非受伤居民消化性溃疡发病率的影响。61家医院，覆盖了该地区所有内镜检查的70%，参加了这项研究，并根据损伤的严重程度分为三个地区，对10家医院进行了比较，831例患者在地震后2个月内进行了上消化道内镜检查，1994年同期在同一医院进行了16，100例，结果：在受灾最严重的地区，尽管内窥镜检查的总数急剧下降，（50.0%），1995年胃溃疡（GU）患者增加，而十二指肠溃疡患者减少，导致胃溃疡与十二指肠溃疡的比例高于1994年1995年GU患者的平均年龄明显高于1994年。坂神淡路地震引起的生活事件应激不仅引发而且加重了GU，尤其是老年人。(C)1998年，我胃肠病学。
Objective: Although physical stresses are known to induce peptic ulcers in the upper gastrointestinal tract, it remains controversial whether emotional stress can cause peptic ulcers, Therefore, we examined retrospectively the influence of the Hanshin-Awaji earthquake that occurred in Japan in January 1995 on the occurrence of peptic ulcer disease among noninjured residents, Methods: Sixty-one hospitals, covering 70% of all endoscopy examinations performed in this area, joined the study and were divided into three areas according to the severity of the damage, A comparison was made between a group of 10,831 patients who underwent upper gastrointestinal endoscopy within 2 months after the earthquake and 16,100 who did so in the same hospitals during the corresponding period in 1994, Results: In the most devastated area, in spite of a dramatic decrease in the total number of endoscopies (50.0%), patients with gastric ulcer (GU) were increased in 1995, whereas those with duodenal ulcer were decreased, resulting in a higher ratio of gastric to duodenal ulcers than in 1994 (3.07 vs 1.88), In particular, there was a marked increase in bleeding GU, The mean age of patients with GU was significantly higher in 1995 than in 1994, Conclusion: The Hanshin-Awaji earthquake-induced life event stress not only triggered but also exacerbated GU, particularly in the elderly. (C) 1998 by Am. Coll. of Gastroenterology.