CANCER RISK AMONG STAFF AT 2 RADIOTHERAPY DEPARTMENTS IN DENMARK
CANCER RISK AMONG STAFF AT 2 RADIOTHERAPY DEPARTMENTS IN DENMARK
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DOI：
10.1259/0007-1285-64-761-455
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发表时间：
1991-05-01
影响因子：
2.6
通讯作者：
STORM, HH
中科院分区：
文献类型：
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作者：
ANDERSSON, M;ENGHOLM, G;STORM, HH
与丹麦一般人群相比，通过与丹麦癌症登记处的联系，评估了1954-1982年期间在丹麦两个放射治疗部门工作并于1968年4月1日存活的工作人员患癌症的相对危险度（RR）。 所有工作人员都接受了胶片剂量计的辐射监测。 研究队列包括4151人，累积49553人-年的风险。 集体辐射剂量为76.54 mSv，平均剂量为18.4 mSv。 共观察到163例癌症病例，预期为152.3例。 通常被认为是放射性的癌症的风险并没有增加。 观察到前列腺癌显著过多（5例，相对危险度，6.02; 95%置信区间，1.94-14.06）;这可能是一个偶然发现。 没有观察到辐射剂量或暴露年数与癌症风险之间的关系，但观察到自第一次暴露以来风险随时间的推移出现微弱的非显著增加。
In comparison with the general Danish population, the relative risk (RR) for cancer among staff members employed in two radiotherapy departments in Denmark during 1954-1982 and alive on 1 April 1968 was assessed by linkage to the Danish Cancer Registry. All staff had been monitored with film dosimeters for exposure to radiation. The study cohort consisted of 4151 persons, accruing 49553 person-years at risk. The collective radiation dose was 76.54 manSv and the mean dose 18.4 mSv. A total of 163 cancer cases were observed with 152.3 expected. The risks for cancers usually considered to be radiogenic were not elevated. A significant excess of prostatic cancer was observed (five cases, relative risk, 6.02; 95% confidence interval, 1.94-14.06); this is likely to be a chance finding. No relation was observed between radiation dose or years of exposure and cancer risk, but a weak non-significant increase in risk with time since first exposure was seen.