CHEMISTRY OF THE VITREOUS HUMOR: II. PROTEOLYSIS
CHEMISTRY OF THE VITREOUS HUMOR: II. PROTEOLYSIS
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玻璃体液的化学：II。
DOI：
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发表时间：
1934
期刊：
影响因子：
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通讯作者：
A. Krause
中科院分区：
文献类型：
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作者：
A. Krause
玻璃体液的蛋白水解与其液化和变性直接相关。蛋白水解以两种方式发生：第一，通过自溶，其可以被定义为玻璃体液中所含的蛋白水解酶的自身消化或水解，以及第二，通过杂解，其可以被定义为玻璃体液通过带入其中的蛋白水解酶的水解。在杂解中，蛋白水解酶主要来自白细胞的崩解，1可能通过迁移或血清渗出物进入玻璃体。血清中含有的不耐热蛋白水解酶抑制剂是玻璃体蛋白杂解的一个因素。这种抑制剂很容易被大量的白细胞克服，特别是在化脓性渗出液中。血清离开血管后，它往往会消失。1尽管尝试
Proteolysis of the vitreous humor is directly associated with its liquefaction and degeneration. The proteolysis takes place in two ways : first, by autolysis, which may be defined as autodigestion or hydrolysis of the vitreous humor by the proteolytic enzymes which are contained in it, and, second, by heterolysis, which may be defined as hydrolysis of the vitreous humor by the proteolytic enzymes which are brought into it. In heterolysis, the proteolytic enzymes arise chiefly from disintegration of the white blood cells,1which may enter the vitreous humor by migration or in the exudates of blood serum. The thermolabile inhibitor for proteolytic enzymes, which is contained in the blood serum, is a factor in heterolysis of the vitreous portein. This inhibitor is easily overcome by abundant white cells, particularly such as occur in suppurative exudates. It tends to disappear after the serum leaves the blood vessels.1 Although attempts