NEUROPSYCHOLOGICAL PERFORMANCE IS RELATED TO CURRENT SOCIAL AND OCCUPATIONAL FUNCTIONING IN VETERANS WITH POSTTRAUMATIC STRESS DISORDER

NEUROPSYCHOLOGICAL PERFORMANCE IS RELATED TO CURRENT SOCIAL AND OCCUPATIONAL FUNCTIONING IN VETERANS WITH POSTTRAUMATIC STRESS DISORDER
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DOI:
10.1002/da.20476
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发表时间:
2009-01-01
影响因子:
7.4
通讯作者:
Westenberg, Herman G. M.
Westenberg, Herman G. M.
中科院分区:
医学1区
文献类型:
--
作者:
Geuze, Elbert;Vermetten, Eric;Westenberg, Herman G. M.

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背景:几项研究报告了创伤后应激障碍(PTSD)患者的即时和延迟言语记忆回忆缺陷。然而,这些研究大多数都存在一些方法学上的缺点。这些研究都没有评估与社会或职业功能相关的参数。方法:对 50 名参加过联合国维和任务的荷兰退伍军人(其中 25 名患有 PTSD,25 名没有 PTSD)进行了全面的神经心理学测试,其中包括韦克斯勒成人智力量表 III、加州言语学习测试和雷伊听觉言语学习测试的四个子测试。患有创伤后应激障碍 (PTSD) 的退伍军人没有药物和药物滥用。结果:患有创伤后应激障碍的退伍军人与对照组相比,总智商得分相似,但表现出图形和逻辑记忆缺陷。患有创伤后应激障碍(PTSD)的退伍军人在学习、即时和延迟言语记忆方面的表现也显着较低。记忆表现准确地预测了当前的社交和职业功能。结论:患有创伤后应激障碍 (PTSD) 的未滥用药物和药物的退伍军人样本中显示出记忆能力缺陷。记忆力缺陷与智商、创伤暴露时间或创伤暴露后的时间无关。这项研究表明,认知表现可以准确预测患有创伤后应激障碍的退伍军人当前的社会和职业功能。抑郁与焦虑 26:7-15, 2009。(c) 2008 Wiley-Liss, Inc.
Background: Several studies have reported deficits in both immediate and delayed recall of verbal memory in patients with posttraumatic stress disorder (PTSD). However, most of these studies bad several methodological disadvantages. None of these studies assessed parameters related to social or occupational functioning. Methods: Fifty Dutch veterans of UN peacekeeping missions (25 with PTSD and 25 without PTSD) were assessed with a comprehensive neuropsychological test battery consisting of four subtests of the Wechsler Adult Intelligence Scale-III, California Verbal-Learning Test, and the Rey Auditory Verbal-Learning Test. Veterans with PTSD were free of medication and substance abuse. Results: Veterans with PTSD bad similar total intelligence quotient scores compared to controls, but displayed deficits of figural and logical memory. Veterans with PTSD also performed significantly lower oil measures of learning and immediate and delayed verbal memory. Memory performance accurately predicted current social and occupational functioning. Conclusions: Deficits of memory performance were displayed in a sample of medication- and substance abuse-free veterans with PTSD. Deficits in memory performance were not related to intelligence quotient, length of trauma exposure, or time since trauma exposure. This study showed that cognitive performance accurately predicted current social and occupational functioning in veterans with PTSD. Depression and Anxiety 26:7-15, 2009. (c) 2008 Wiley-Liss, Inc.